side effects of meloxicam for dogs

Side Effects Of Meloxicam For Dogs & Alternatives

Side Effects Of Meloxicam For Dogs & Alternatives

If you have a pet dog, then you may have already seen the drug Meloxicam in stores. It’s typically sold by its brand name Metacam and is often bought by dog owners who want their pets to get better from certain illnesses and disorders. Keep in mind that the brand Mobic, which is also a Meloxicam medication, is only for humans. Hence, you should never give it to your pet.

What Is Meloxicam for Dogs?

Meloxicam is a medication that is used to reduce inflammation, stiffness, and pain in dogs that have osteoarthritis and similar conditions. It’s also used to treat the symptoms of bone or muscle disorders. It reduces the hormones that cause inflammation and pain.

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID). It has been approved by the Food and Drug Administration (FDA) and can be obtained with a prescription from a veterinarian.

Aside from treating various conditions, it can also be used to alleviate the pain caused by a surgical procedure. So, if your dog needs to undergo a surgery, the veterinarian may recommend and prescribe the drug. Likewise, it may be used to alleviate the pain caused by an injury.

When this happens, see to it that you abide by the guidelines for dosages and proper storage for the drug. You should also know about the possible side effects of meloxicam in dogs. This way, you can be prepared when it comes to dealing with any signs and symptoms.

Dosage of Meloxicam

Usually, the initial dosage given to dogs ranges from 0.09 to 0.1 milligram per pound. Then, this dosage increases to 0.045 to 0.05 milligram per pound. Meloxicam has to be given to the dog orally once per day.

The veterinarian of your dog would give you guidelines and instructions with regard to the proper measurement of its medication. You can give your dog tablets with or without food. However, you need to make sure that he drinks sufficient amounts of water every day.

Aside from tablets, you can also purchase Metacam in liquid form. You can add this liquid medication to the food of your dog if he is not inclined to taking tablets. Consult your veterinarian regarding the most ideal form of Meloxicam.

The veterinarian may also adjust the dosage of your dog based on his response to the medication. Ideally, you should give your pet the lowest possible dosage and still be able to relieve its unpleasant symptoms.

In addition, you can find Meloxicam in injectable solutions. Your dog’s veterinarian would give you guidelines and instructions on how to properly and safely administer this solution.

See to it that you always follow the prescribed dosage of your dog’s veterinarian. Otherwise, you can risk overdosing your pet. This can have unpleasant results, such as dizziness, vomiting, headache, fainting, seizures, slowed breathing, and cardiac arrest among others.


Side Effects of Meloxicam in Dogs

Your dog can experience negative side effects if it takes too much Meloxicam or its body does not properly adapt to the drug. Gastrointestinal upset is the most common side effect of Meloxicam.

If you notice the symptoms getting worse, you have to contact the veterinarian right away. Your dog may either be given an adjusted dosage or an alternative treatment method.

Aside from gastrointestinal upset, your dog may also experience the following side effects after taking Meloxicam: bloody vomit, bloody or black stool, weight gain or swelling due to fluid retention, fatigue, increased urination, increased thirst, yellowing of eyes, skin, and gums, itchiness, weight loss, abdominal pain, stomach ulcers, and changes in behavior.

Furthermore, your dog may have a risk of allergic reaction, which can result in anaphylaxis. So, if you notice any signs of allergic reaction, such as hives, swelling, and difficulty breathing, you must contact the veterinarian right away.

Pregnant dogs as well as puppies should not be allowed to take this drug. Do not forget to tell your dog’s veterinarian about any existing medical condition, especially if it is cardiovascular or renal.

The veterinarian must also be aware of any other medications that you give your dog. Take note that any drug, including over-the-counter ones, may have a negative reaction towards Meloxicam.

Cost of Meloxicam

Meloxicam is actually one of the most affordable medications for alleviating pain and inflammation. Nonetheless, its price may vary depending on where you bought it. You can buy Metacam online and in local stores. It’s generally sold per tablet at $0.51 to $0.73. Each tablet is typically 7.5mg.

For instance, you can check out Heartland Vet Supply as well as KVSupply for stocks and prices.


Interaction with Other Drugs

When you give Meloxicam to your dog, you have to refrain from giving it other types of medication, including prednisone, tramcinolone, dexamethasone, and cortisone among other corticosteroids and NSAID’s.

Make sure that you inform the veterinarian if you have given your dog etodolac, piroxicam, carprofen, furosemide, warfarin, or any over-the-counter drug for cough, pain, cold, or allergy.

Ingredients In Meloxicam

Every milliliter of Metacam (Meloxicam) tablet contains 0.5 to 1.5 milligrams of meloxicam and 1.5 milligrams of sodium benzoate. Its suspension formulation smells like honey and is yellowish in color. Non active ingredients may include silicon dioxide, sodium benzoate, sorbitol, glycerin, saccharin sodium, xylitol, and citric acid monohydrate.

Meloxicam Alternatives

As you know, Meloxicam can have unpleasant side effects. Hence, you should consider alternative treatment methods that have natural healing properties.

Acupuncture – It is not only good for humans, but it is ideal for dogs as well. This Chinese treatment method can help relieve chronic pain and acute pain that is associated with degenerative joint and bone conditions as well as osteoarthritis.

Turmeric – It has natural antioxidant and anti-inflammatory properties that makes it effective in relieving pain. It is also ideal for treating joint conditions such as arthritis.

Yuca – According to holistic veterinarians, this root has a fifty to eighty percent success rate in treating rheumatoid arthritis and osteoarthritis in dogs. It can provide relief for joint inflammation and pain.

CBD Oil – For years, dog owners have turned to CBD oil for relieving various ailments in their pets. CBD oil is actually effective in relieving arthritis and joint pain, relieving anxiety, and reducing inflammation. It is also effective in reducing vomiting and nausea, suppressing muscle spasms, reducing seizures, and improving sleep.

Moreover, it is effective in improving appetite as well as improving nervous system and digestive health. With this being said, you can conclude that CBD oil is a much better alternative to prescription drugs, such as Metoxicam, in many ways.

Due to its natural healing properties, your pet can avoid experiencing unpleasant side effects and adverse reactions to unnatural ingredients. Holistic alternatives can be just as good as prescription medication, but without the harsh side effects.


side effects aspirin for dogs

Side Effects of Aspirin For Dogs & Alternatives

Aspirin for Dogs: Uses, Side Effects, Dosage, and Best Alternatives

A dog in pain because of an injury or illness is a painful sight for owners. There are many ways to relieve a dog’s pain. One of these solutions is using aspirin.

Aspirin is a type of anti-inflammatory medication similar to ibuprofen and carprofen. Vets prescribe aspirin for dogs with a certain dosage. It’s used to treat fever, inflammation, and pain. It can also prevent blood clots.

Aspirin For Dogs Dosage

It’s best to leave the dosage calculation of aspirin to your veterinarian. Your vet knows your dog’s medical history and can give the right amount of aspirin to avoid unwanted side effects. He/She would also know if your dog can or can’t take aspirin.

There’s a general guide to know if your dog is getting the right dosage. It’s usually based on weight.

Weight of Dog Aspirin Dosage
0-5 lbs. 25-50 mg.
5-10 lbs. 50-100 mg.
10-20 lbs. 100-200 mg.
20-40 lbs. 200-400 mg.
40-60 lbs. 300-600 mg.
60-80 lbs. 400-800 mg.
80+ lbs. 500-1000 mg.


You mustn’t give any aspirin to your dog if you have yet to take him to the vet. This dosage table is just a guide to see if your dog is getting enough or too much aspirin. The dosage may still differ depending on your dog’s case.

In case you miss a dose, you can do two things. First, if the dose is not too late, give it as soon as possible. And second, skip the missed dose and continue with your dog’s regular schedule. Don’t give him twice the dosage if he misses one because doing so can lead to overdose.

Aspirin for Dogs Side Effects

Even though aspirin is an OTC (over-the-counter) drug, it’s best to consult a vet before giving it to your dog. Your vet may only prescribe aspirin for limited time because it has unwanted side effects. Some of these side effects include:

  • Vomiting
  • Ulcer
  • Diarrhea and/or black stool
  • Change in appetite
  • Seizures
  • Thinning of the blood
  • Mucosal erosion

In worse cases, a dog can experience overdose and would result in these side effects:

  • Abnormalities caused by acid
  • Coma
  • Hemorrhage
  • Liver or kidney disease
  • Death

Aspirin Cost

The price of aspirin may differ from the brand, dosage, and quantity per bottle. A bottle of chewable aspirin tablets may not go over $20. It would also depend on the drug store or vet clinic you buy it from.

Interaction of Aspirin with Other Drugs

Aspirin can have a negative interaction with certain drugs. This is another reason for you to not give your dog. Here are some drugs that can react with aspirin:

  • Anti-coagulants
  • Catropil
  • Digoxin
  • Enalapril
  • Furosemide
  • Gentamycin
  • Insulin
  • Other anti-inflammatory drugs
  • Drugs that can cause ulcers

You should always inform your vet about the medications your dog is currently taking. This will avoid any unfortunate side effects in case the vet prescribes aspirin.

Ingredients in Aspirin for Dogs

The active ingredient for all aspirin for dogs is aspirin or acetylsalicylic acid. Some brands of aspirin have inactive ingredients like powdered cellulose, corn starch, and triacetin. Some have flavorings to make it appetizing to take for pets.

Aspirin Alternatives

As a pet owner, all you want is the best for your pet. Since aspirin has harmful side effects, you may want to go for alternatives with the same benefits with little to no side effects.

Instead of giving your dog medications, you can give him natural sources with anti-inflammatory properties. Some of these include:

  • Fish oil. It can relieve a dog’s inflammation caused by arthritis, bowel diseases, and allergies. Besides pain relief, it’s a good way to help your pet cope with kidney diseases which can become worse with aspirin.
  • Extra-virgin coconut oil. This natural painkiller has properties similar to aspirin. It can reduce inflammation in your dog’s body resulting in pain relief.
  • Spices. Some spices like turmeric, rosemary, and ginger can also reduce inflammation. They have polyphenols and bioflavonoids which are natural anti-inflammatory compounds.
  • Fruits. Blueberries, mangoes, apples, and blackberries also have natural anti-inflammatory properties. They contain vitamins, flavonoids, and carotenoids. These are not only great for pain-relief, but they can also support your dog’s recovery.
  • Whole grains. These include barley, brown rice, and oatmeal. They can lower C-reactive protein (CRP) levels in your dog’s blood. CRP is responsible for many inflammation-related diseases.
  • Dark leafy vegetables. Certain vegetables especially ones with dark leaves have vitamin C, carotenoids, and anti-oxidants. These are great pain relievers for your dog.

These natural pain relievers are better alternatives to aspirin for dogs. They won’t have any harmful side effects. They also have many health benefits besides pain relief.

However, they may not take effect quickly, which is typical of many natural remedies.

CBD Oil as an Alternative to Aspirin

Luckily, there’s another alternative to aspirin that you can use for your dogs. CBD’s popularity is continuing to grow because of its numerous health benefits for humans. However, many studies have found that it can benefit animals like dogs as well.

Like aspirin, CBD oil can give pain-relieving effects which improves your pet’s day to day life especially if they have conditions that bring chronic pain.

CBD has anti-inflammatory properties that can relieve pain and swelling. This can be great for dogs suffering from arthritis. It may also help reduce chronic joint and back pains because of old age.

In addition, CBD is known to have muscle relaxant and mood enhancing effects.

Using CBD oil for dogs may have side effects though. These include dry mouth, low blood pressure, and drowsiness. But, these side effects aren’t as harmful as the side effects of aspirin.

Unlike the other natural pain relievers, CBD oil can take effect after a few minutes of using. This is the same with aspirin with less negative side effects.


Aspirin can help dogs go through painful injuries and diseases as they recover. But, it’s important to know that it can have harmful side effects. You mustn’t give aspirin to your dog without a vet’s prescription.

Also, there are better alternatives to aspirin that won’t have any negative effects. You can give your dog foods that have natural anti-inflammatory properties. You may also resort to CBD oil which takes a few minutes to take effect but comes without the harmful side effects that aspirin has.



Side effects of metacam for dogs

Side Effects of Metacam For Dogs & Alternatives

Side Effects of Metacam For Dogs & Alternatives

What is Metacam for Dogs?

Metacam or Meloxicam is a non-steroidal anti-inflammatory drug (NSAID). This is used to treat stiffness, inflammation, and pain in dogs. Metacam is also used to reduce fever.

Metacam’s effect is seen 8 hours after administration. If giving the dog Metacam for the first time, it may take 3-4 days to take effect. Stop giving the drug if after 10 days there is still no improvement on the dog’s condition.

Dosage of Metacam

Oral suspension Metacam is given 0.2 mg Metacam per kilogram of body weight on the first dose. The following doses or maintenance dose is 0.1 mg per kilogram of body weight.

The oral suspension Metacam should be given with food. This oral suspension type come in 10, 32, 100 or 180 mL bottles.

Metacam tablet form is in 7.5 mg dosage and can be given with or without food. The initial dose is 0.1 mg per pound of body weight. After that, the dose will be 0.05 mg per pound of body weight.

Metacam is given to the dog once a day.

For dogs that are less than 10 pounds, Metacam should be given with food. Never administer the drug directly into the dog’s mouth. The dose is two drops per pound of body weight. This is for the 0.5 mg per mL concentration.

For dogs over 10 pounds (4.5 kilograms) use the measuring syringe provided. This is designed to administer the daily maintenance dose which is 0.05 mg/lb.

To get the accurate dosage per the dog’s body weight, round off the dog’s weight to the nearest 1 pound increment.


Metacam should not be given to dogs aged 6 weeks and below. Lactating, breeding and pregnant dogs should not be given Metacam.

Dogs with existing cardiovascular diseases and renal conditions should not be given Metacam. This can cause further complications on the dog.

It is important to tell your veterinarian about the medications the dog is taking in. This is to prevent harmful drug interactions from happening.

Side effects Metacam for dogs

NSAIDs such as Metacam can affect the kidney and liver of the dog in long term use.

Other side effects of Metacam are:

  • Blood in vomit
  • Weight loss
  • Itchiness
  • Behavioral changes
  • Stomach ulcers
  • Black or bloody stool
  • Fatigue or weakness
  • Swelling or weight gain- this is due to fluid retention
  • Abdominal pain or tenderness
  • Increased thirst
  • Increased urination
  • Jaundice- yellowing of the eye, skin, and gums

There are reported cases of allergic reactions as well. In a worst case scenario these allergic reactions can lead to anaphylaxis. Anaphylaxis happens when the airway constricts preventing oxygen to be distributed to the lungs.

Metacam storage

Metacam should be stored at a controlled room temperature. The temperature should be between 59 degrees and 86 degrees Fahrenheit.

Metacam Cost

  • A bottle of Metacam that is 1.5 mL/32 mL cost around 57 dollars. A 100 mL bottle cost around 120 dollars.
  • A bottle of 180 mL Metacam is around 136 to 175.69 dollars.
  • A bottle of 1.5 mL/10 mL Metacam cost around 15 dollars.


Interaction of Metacam to other drugs

Metacam should not be given with other NSAIDs. These include Firocoxib, Aspirin and Carprofen. This can inhibit the function of and normal response of the medication to the dog’s body.

Corticosteroids such as prednisone and cortisone should be avoided when the dog is taking in Metacam. Corticosteroids can make the side effects of Metacam worst.

Active Ingredients of Metacam

The active ingredient of Metacam is meloxicam. A bottle of Metacam has 1.5 mg of meloxicam. It also contains 1.5 mg of sodium benzoate. This is equivalent to 0.05 milligrams per drop.

Other ingredients include sodium citrate dihydrate colloidal silicon dioxide, povidone, microcrystalline cellulose and magnesium stearate.

Oral suspension Metacam substances are suspended in a yellowish solution with an odor of honey.

Metacam alternatives

Metacam is an effective drug for dog pain. There are also other natural remedies for dog pain and stiffness.

Keeping the dog in a healthy lifestyle is one that helps. This includes proper diet and regular exercise.

The following are some anti-inflammatory and pain remedies:

Fish oil – Fish oil helps with pain and inflammation. Fish oil has omega 3 that reduces inflammatory substances in the dog’s body.

Arnica – Arnica is a plant that is mostly grown in Europe and North America. Arnica is extracted from the flowers.  The compounds inside the plant help treat inflammation.

There are different forms of arnica. It can be in oil, gel, or capsule variants.

Hydrotherapy- This therapy involves the dog swimming in a purpose-built pool. This helps ease pain for dogs with stiff joints. Hydrotherapy also helps build muscle mass to support the joints.

Glucosamine – This is a popular anti-inflammatory remedy. Glucosamine is mainly used for joint problems. This includes joint inflammation/ pain, arthritis and dysplasia.

Glucosamine helps ease issues in the digestive system.  Glucosamine treats joint inflammation by producing more synovial fluid and cartilage.

Yucca – Yucca is an anti-inflammatory plant grows in Central and South America. Yucca contains saponins found in the roots of the plant. Saponin substances are as effective as some steroid medications. This compound is the one that reduces inflammation.

Yucca is an effective remedy but it can irritate the stomach. Yucca is not for long-term use. It works best with minor conditions.

Acupuncture – Acupuncture is a traditional Chinese medical practice. This involves inserting small hair-like needles into the skin.The needles are inserted in the part to be treated. This are called acupuncture points.  This helps reduce inflammation, ease pain and improve overall health of the dog.

CBD oil – CBD stands for Cannabidiol. This is also known as hemp oil.  CBD oil is one of the known and effective alternatives for Metacam.

It is considered safe because it is derived from the hemp plant. This oil extract helps solve inflammation issues by activating the endocannabinoid system of the dog.

CBD is also used to treat colitis, gastritis, dysplasia’s, inflammatory bowel disease (IBD), and arthritis.

CBD oil also provides protection against diabetes and tumor growth.



ibuprofen for dogs

Side Effects Of Ibuprofen For Dogs & Alternatives

Side Effects Of Ibuprofen For Dogs & Alternatives

Seeing your dog in pain is upsetting. Your primary concern is to find an immediate solution to alleviate the pain. Sometimes, you tend to use over-the-counter (OTC) pain medications that only work on humans. This can put your pet in so much danger. It can lead to more serious complications and death.

To prevent this, always consult your vet about the right medications to use. Do not use OTC pain meds specifically for human consumption.

What is Ibuprofen for Dogs

Ibuprofen is a Nonsteroidal Anti-inflammatory Drug (NSAID) that is mainly used to treat pain and inflammation in humans. It can also be used to treat headache, fever, and arthritis. In humans, Ibuprofen works by inhibiting cyclooxygenase, an enzyme that produces prostaglandins. These enzymes bring fever-like symptoms like pain and inflammation. Prostaglandin-inhibiting drugs like Ibuprofen help relieve these symptoms.

Veterinarians do not recommend the use Ibuprofen in dogs since it can cause adverse reactions to canines. Dogs can also get easily overdosed by Ibuprofen. Prostaglandins play important roles in a canine’s body such as normal blood clotting and good blood flow to the kidneys. These enzymes also help protect the gastrointestinal tract (GI) of a dog. When dogs ingest Ibuprofen, the drug will destroy the prostaglandin enzymes that are beneficial to dogs.

Dosage of Ibuprofen

Normally, the vet does not prescribe and administer Ibuprofen medication to dogs. But in some special cases like eye inflammation, the pain brought by cancer, and arthritis, they give a really small dose of Ibuprofen. The usual drug dosage is 2.5 mg – 4 mg per 5-8 kg twice a day or every 12 hours. It should strictly given by the doctor, do not attempt to do it yourself

Side Effects of Ibuprofen

Ibuprofen, when ingested by dogs, spreads rapidly in the bloodstream. The components of this drug are easily absorbed in their stomach and intestines. Within a short period, your dog may experience allergic reactions and other symptoms.

The following are the side effects of Ibuprofen in dogs:

  • Gastrointestinal bleeding
  • Vomiting
  • Loss of appetite
  • Abdominal pain
  • Irregular bleeding
  • Pale gums
  • Liver and kidney failure (extreme cases)

When the owners accidentally give higher doses of Ibuprofen to their canine, this can lead to:

  • Change in behavior
  • Altered mental status
  • Episodes of seizure attacks
  • Coma
  • Death

Cost of Ibuprofen

A single 200-mg Ibuprofen oral capsule costs $1 – $2.13. A single 100-mg oral tablet costs $1.15 while a 200-mg oral tablet costs $1.35. One bottle of Ibuprofen oral drops (40mg/ml) costs $6.50-$8.30 while oral suspension (50mg/1.25ml) costs $11.50 – $12.

Interaction with Other Drugs

If your vet prescribed Ibuprofen to your canine, listen attentively to his instructions. Take note of the following:

  • Administering Ibuprofen with anticoagulants can be dangerous. Doing so will prolong the prothrombin time that can lead to bleeding.
  • Taking this drug with Cholestyramine may decrease its effect.
  • When used with Cyclosporine, this can damage the kidneys.
  • When Ibuprofen is mixed with diuretics, the diuretic med could be rendered ineffective.
  • Ibuprofen and Phenobarbital combination can reduce Ibuprofen’s effect.
  • Probenecid can increase the plasma concentration of Ibuprofen.

Ingredients in Ibuprofen

Ibuprofen contains the active ingredient Ibuprofen, a water-soluble substance. This NSAID is readily soluble in organic solvents like acetone and ethanol. Other inactive ingredients include hypromellose, colloidal silicon dioxide, magnesium stearate, and lactose monohydrate. As stated above, Ibuprofen is a prostaglandin-inhibiting drug. It also possesses antipyretic (anti-fever) and analgesic properties. Most components of Ibuprofen drug are dangerous to dogs and cats.

Ibuprofen Alternatives

As a dog owner, it is best to find the best alternative solution to help relieve your pup’s pain. Eliminating Ibuprofen as an alternative is one of the best solutions to do this. You can use the following Ibuprofen alternatives:

  1. NSAIDs for Dogs
  • Your vet will only use Ibuprofen to treat your dog’s pain if badly needed. Otherwise, he will prescribe the following NSAIDs that are specifically made for dogs:
  • Deramaxx
  • Rimadyl’
  • Previcox
  • Metacam
  • Tramadol
  • Amantadine
  • Gabapentin

If the pain seem tolerable, you can use more natural ways such as gentle massage and other therapies.

  1. Omega-3 fatty acids – Omega-3 are healthy fats that come from these fish sources – salmon, tuna, mackerel, herring, etc. These unique fatty acids act directly in different human and animal cells to relieve inflammation. Less inflammation can lead to decreased swelling, redness, and pain. Since most dogs love to eat fish meat, it can be a good alternative pain management solution for your canine.
  2. Joint Supplements – Joint supplements are one of the most effective chronic pain management for joint ailments such as arthritis in dogs. The most common joint supplement is glucosamine. This is a chondroprotective medication that cushions the cartilage while the body is trying to repair cartilage loss. Protecting cartilage means decreasing the pain and inflammation. Joint supplements like glucosamine, are administered orally.
  3. Acupuncture – This traditional Chinese medicine can help relieve muscle and joint pain, inflammation, and trauma. This can provide temporary or permanent pain solution to your canine. When thin needles are inserted to your pet’s body, it stimulates the nervous system and improves its blood circulation. Then, it releases good hormones that help soothe the pain and discomfort. Consult a licensed animal acupuncturist to do this.
  4. CBD Oil for Dogs – Cannabidiol (CBD) oil is a hemp plant extract that is becoming popular nowadays. The good thing about CBD oil is it is not psychoactive and is safe to your dogs. It only contains 0.3% of Tetrahydrocannabinol (THC) that brings psychological effects. This does not make your dogs “high”; instead, this can make them feel more relaxed and pain-free.
  • CBD oil contains a good amount of anti-inflammatory compound that helps stop inflammation or swelling. The presence of inflammation indicates pain.

Dog illnesses such as chronic cancer, arthritis, and severe joint injury can be extremely painful for your best buds. CBD oil acts directly to the affected site and provides immediate relief. This hemp extract can also help stabilize the mood of your canine and make him feel more relaxed. When your dog feels good, the pain can be eliminated quickly. Your best friend can now go back to his daily routines and be alive again.

  • To administer CBD oil to your dogs, use the following techniques:
  • Applying directly to your dog’s mouth
  • Incorporating to a treat
  • Mixing with foods and drinks

Your canine’s health is always a priority. Regularly check your pet for any pain and discomfort. Pain can be irritating to dogs. This too can change his behaviors and interactions with humans. When giving pain medications, try to avoid NSAIDs that can put your pup in danger. You should not administer Ibuprofen to your dog in any means. Your vet will decide whether to give this drug or not to your canine.

Using CBD oil is one of the best alternative pain treatments for your dogs. This hemp extract contains natural anti-inflammatory and analgesic properties. This also helps your canine feel more relaxed and stress-free. Cannabidiol is safe to use and effective if taken in the right dosage. For best results, consult your vet.


Rimadyl for dogs side effects alternatives

Rimadyl For Dogs Side Effects & Rimadyl Alternatives

Side Effects Of Rimadyl For Dogs & Alternatives: Everything You Need to Know

Rimadyl (Carprofen) is a non-steroidal anti-inflammatory drug (NSAID), meaning it’s designed to relieve pain and inflammation. It’s often used in managing cases of canine osteoarthritis.

Note that the drug can also be used in the treatment of other joint conditions, such as hip dysplasia. It may likewise be given after a surgical or dental procedure to reduce both fever and pain.

What is Rimadyl for Dogs?

Rimadyl comes in caplet, injection, and chewable forms. However, it should only be given to dogs that are more than six weeks of age and with the advice of a veterinarian.

If you’re like most other concerned pooch owners, you’re probably wondering about the specifics of this drug—especially in relation to the various conditions for which it’s given.


Osteoarthritis occurs when cartilage in the joints wear off. This condition is most often diagnosed among dogs of advanced age. Its common symptoms include lameness, stiffness, and/or limping [1].

Simply put, Rimadyl helps reduce the pain, while also alleviating the inflammation that occurs when the bones scratch onto each other due to the thinning of the cartilage between them.

Hip Dysplasia – Hip dysplasia is a condition where the dog’s hip bones don’t form properly. The hip joint normally glides as the dog moves. In hip dysplasia, the bone grinds, causing significant amounts of pain.

This condition usually affects larger dogs such as Labradors, German Shepherds, Great Danes, and Saint Bernards [2]. A vet prescribes Rimadyl to ease the discomfort and reduce fever associated with hip dysplasia.

Pain (Surgery) – Dogs, just like people, experience pain after a surgical or dental procedure. Rimadyl may be given to alleviate that pain. Likewise, it may be prescribed to manage fevers that occur post-surgery.

Dosage of Rimadyl

Caplets and chewable tablets are in 25-, 75-, and 100-milligram doses. The usual prescribed dosage is 2 milligrams per pound of body weight. This is to be given once daily.

Sometimes, the veterinarian spreads out the dose, setting it at 1 milligram per pound of body weight. This is then to be given twice daily [3]. With injectables, the dose is 4.4 milliliters per kilogram body weight, given daily.

There’s a chance for a pooch to find itself gaining access to the NSAID and start gobbling it up. Rimadyl is liver-flavored, after all, which most canine companions love. If ever this happens, the signs of overdose may manifest:

  • Excessive vomiting
  • Blood in stools or vomit
  • Lethargy
  • Seizures
  • Excessive vomiting
  • Extreme abdominal pain

If you see any of the said signs in your dog, bring him to the vet right away.

Rimadyl For Dogs Side Effects

Rimadyl is a safe medication, assuming that it’s used for the right conditions and at the right doses. But like other drugs, it can cause certain side effects [4], including:

  • Diarrhea
  • Vomiting
  • Fatigue
  • Black, bloody or tarry stool
  • Constipation
  • Seizures
  • Muscle cramps
  • Gastrointestinal ulcers
  • Weakness
  • Sores in the mouth
  • Fluid retention
  • Behavioral changes
  • Abdominal pain
  • Extreme thirst
  • Weight gain
  • Decreased thirst
  • Jaundice (yellowing of the skin and gums, as well as the whites of the eyes)
  • Urinary abnormalities

In extreme cases, it can also lead to kidney and liver problems.

Keep in mind that Rimadyl is not for every dog with joint pain, which is why it’s important to keep your pooch’s current veterinarian fully informed. It must never be given to canines that have the following conditions:

  • Allergy to aspirin
  • Allergy to NSAID
  • Kidney disease
  • Congestive heart failure
  • Pre-existing ulcer
  • Liver disease
  • Heart disease
  • Bleeding disorders
  • High blood pressure

Rimadyl should not be taken by dogs below two and a half months old. As to be expected, it also isn’t advised to give this drug to any dog that’s pregnant or lactating.

Cost of Rimadyl

A 100-milligram tablet costs around 0.75-0.85 cents. On the other hand, 30 pieces of 25-milligram chewable tablets cost anywhere from 25 to 30 dollars. A 60-tablet pack will be priced at around 56 to 80 dollars.

Interaction with other Drugs

Rimadyl should not be given together with corticosteroids and other NSAIDs. This causes gastrointestinal problems and bleeding, aside from increasing the side effects of Rimadyl itself.

Anti-hypertension drugs, such as Abediterol and Acebutolol, should not be given in-line with Rimadyl. This combination ultimately increases the severity of hypertension.

Lastly, the drug must not to be given with ACE inhibitors such as Enelapril and Benazepril [5]. Ace inhibitors rely on the dilation of blood vessels and can interfere with the function of NSAIDs.

Ingredients in Rimadyl

The active ingredient in this NSAID is Carprofen, which varies in amount depending on the dose of the tablet. There’s one other noteworthy ingredient—the flavoring. As mentioned, Rimadyl has a liver-like flavor.

Rimadyl Alternatives

At this point, it should be clear that Rimadyl isn’t without flaw. And so, it’s only appropriate to ask whether there are alternatives that may be considered. Well, here’s a list of the most popular ones:

Dasuquin  – Dasuquin is a natural supplement. It contains MSM, glucosamine, chondroitin, and essential compounds that are abundant in avocado and soybean.

This supplement is effective in strengthening dog joints. It also helps prevent canines from developing osteoporosis and other similar bone or joint issues.

Tramadol and Adequan – These two are effective in reducing inflammation and swelling in the joints [6]. These can likewise be used to reduce pain, especially after a dental or surgical procedure.


Concentrated Omega 3- This supplement aids in alleviating pain, swelling, and inflammation. It’s available in both capsule and liquid forms, but all omega-3 supplements are given to dogs orally.


Cannabidiol (CBD Oil) – CBD oil or Cannabidiol is also known as hemp oil. Since this is from a plant, it’s natural and a safer alternative to NSAIDs [7]. And yes, CBD oil is actually among the best natural substitutes to Rimadyl.


Cannabidiol is used for lot of conditions, even those that affect mood. It’s even given for the sake of strengthening the heart. This supplement is most known, however, for its capacity to address cancer-related issues.


CBD oil may be given to reduce pain after a surgical procedure. This is safe to use and can be given even to older-aged dogs. This supplement can still cause some side effects though, like appetite changes, fatigue, and diarrhea.

Rimadyl isn’t Always Good Enough

There’s no denying that in most cases of pain and inflammation, Rimadyl should work sufficiently well. However, with the risks and downsides that it comes with, many dog owners opt for safer options—one of which, is CBD.




carprofen for dogs side effects

Side Effects Of Carprofen For Dogs & Alternatives

Side Effects Of Carprofen For Dogs & Alternatives: What is Carprofen for Dogs?

Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic properties. It is used solely in veterinary medicine for treating dogs with arthritis and for postoperative pain.

People also used Carprofen during the 1980s but for commercial reasons, the manufacturer withdrew it from the market, effectively terminating the use of the drug for human treatment.

It’s important to note that the drug does not cause cancer. In a two-year oral toxicity study and an 80-week carcinogenicity study, Carprofen was found to exhibit no carcinogenic potential.

Dosage of Carprofen

When prescribing Carprofen, vets consider both its benefits and risks. To be on the safe side, they often give the minimum effective dosage within the shortest duration possible based on individual response.

In most cases, however, the recommended dose is 2 mg/lb of body weight daily. This can be divided into two daily doses of 1 mg/lb body weight to be given twice daily.

For controlling pain associated with surgery, the drug is usually administered two hours prior to the procedure.

Carprofen is available in capsule as well as tablet forms, in 25, 75, and 100 mg doses. A bottle may contain 30, 60, or 180 capsules depending on size.

Side Effects of Carprofen

There are no clinically significant adverse reactions reported for this NSAID.

In studies, low frequencies of adverse reactions were observed: constipation (3%), behavioral changes (1%), lethargy (1.4%), changes in appetite (3%), diarrhea (4%), and vomiting (4%).

Dogs respond well to the medication. However, like all NSAIDs, prolonged use can result to liver, gastrointestinal, and kidney problems.

Even by staying within the prescribed dose and duration, your canine companion may still experience loss of appetite and loss of coordination. Other side effects to watch out for include:

  • Increase in thirst
  • Seizures
  • Increase in urination
  • Liver dysfunction characterized by yellowing of eyes
  • Partial or full paralysis
  • Skin changes (scabs, redness, etc.)

Effects recorded for Carprofen overdose include ulcer formation and gastritis. Use the drug with caution if your dog has liver or kidney disease, and in cases of dehydration or bleeding.

The safety of Carprofen has not been established for dogs with bleeding disorders, and for those that are pregnant, or used for breeding purposes, as well as in lactating dogs.

Before using Carprofen, confirm with the vet if your dog has an allergic reaction to aspirin. If such is the case, the vet will most likely avoid prescribing the NSAID.

The same goes for allergic reactions to other NSAIDs such as Tepoxalin and Meloxicam. Allergic reactions result to symptoms such as red or itchy skin, hives, or facial swelling.

Cost of Carprofen

Carprofen is a prescription, non-DEA controlled substance. As in the case of other drugs, it’s safe to use the generic equivalent of branded Carprofen. Yes, you’re going to enjoy lots of savings too if you go generic.

The generic form is cheaper because manufacturers do not have to do the same costly laboratory clinical trials that brand-name companies go through to get FDA approval.

No worries with the generic type, however, as it carries the same active ingredient, has the same strength, and is equally safe. Still, ask your vet if he’s recommending a particular brand.

Now for the price, you will spend less than $0.40 per 75-mg pill if you go for generics.

Some generic medicine vendors offer free shipping for a certain minimum amount of order—for example, free shipping for a total purchase of $49. The lowest price is $0.29, which is for 25-mg pills.

Prices for branded varieties like Novox will almost double your expenses. With Novox, you will spend about $0.75 to $0.89 per pill, depending on the supplier. This usually comes with a free shipping offer though.

Other brand names include Rimadyl, Acticarp, Carprieve, and Vetprofen.

Interaction with other Drugs

There are several drugs that interact with Carprofen:

  • Phenytoin – an anti-epileptic drug
  • Valproic acid – also for treating epilepsy and bipolar order
  • Oral anticoagulants – these are blood thinners to reduce risk for stroke
  • Salicylates – examples of these are Acetaminophen and Ibuprofen
  • Sulfonamides – these are drugs that inhibit bacterial growth
  • Sulfonyurea – used in drugs to control diabetes
  • Phobenecid – a drug that increases uric acid secretion
  • Methotrexate – also called antimetabolites; used to treat certain types of cancer, psoriasis, and rheumatoid arthritis
  • Furosemide – used to reduce abnormally high body fluids
  • Digoxin – used to treat atrial fibrillation
  • Glucocorticoids – these are a class of steroid hormones

If you’re unsure of the content of the drugs that your dogs are currently taking, consult your vet.

Ingredients in Carprofen

Depending on the brand, a Carprofen tablet or pill may also contain the following ingredients:

  • Microcrystalline cellulose
  • Croscarmellose sodium
  • Magnesium stearate
  • Purified stearic acid

How much of these other ingredients are included in a given tablet or pill? Well, the specific formula for each variety of the NSAID is maintained as a trade secret by manufacturers.

Carprofen Alternatives

Consider these alternative treatment options in the event of an emergency and in cases when Carprofen is beyond your reach or simply not suited for your pooch:

  • CBD Oil – This is by far the best alternative there is to Carprofen, with some dog owners even attesting that CBD oil is the safest treatment one can consider for a wide range of diseases.

Aside from pain related to arthritis, canine health issues that can be treated include gastrointestinal diseases, symptoms of cancer, anxiety, stress, nausea, and seizures.

Other reasons for using CBD Oil include: improvement of skin and coat, weight and metabolism support, and lowered risk of cardiovascular disease.

However, keep in mind that drowsiness, reduced blood pressure, and dry mouth should be regularly checked for in dogs that are given this natural NSAID substitute.

  • Deracoxib – Like other NSAIDs, this is indicated for pain and inflammation associated with orthopedic surgery and should not be used on pups younger than four months. Vomiting, decreased appetite, and change in bowel movement are its common side effects.
  • Meloxicam – This is given to ease pain, inflammation, and stiffness stemming from musculoskeletal system disorders. Its side effects include appetite loss, diarrhea, loss of coordination, and skin irritation.


tramadol for dogs side effects

Tramadol For Dogs Side Effects Tramadol & Alternatives

Side Effects of Tramadol For Dogs & Alternatives

It can be flustering not to know what to do when your dog needs your help, especially when they’re down with pain. The most automatic response is to go to the vet and, without any question, buy whatever painkiller is in the prescription. Following the prescription strictly is not unwise. However, it’s better to think about your dog’s medication more extensively before settling with a painkiller. This is most important if your dog is suffering from chronic pain.

One of the painkillers you should think twice about is Tramadol. Though Tramadol can give your dog fast-acting and long-lasting relief, it isn’t formulated to be safe for long-term use. In the following post, you’ll learn all about Tramadol and why you should be cautious in giving them to your dogs.

What Is Tramadol for Dogs?

Tramadol is the generic name for a kind of opioid drug. It is medically used as a narcotic analgesic for relieving moderate to severe pain in both humans and dogs.

This kind of painkiller can be prescribed for dogs who are suffering from acute and chronic pain caused by any of the following conditions:

  • Post-operative pain
  • Physical injury
  • Cancer symptoms
  • Osteoarthritis
  • Hip dysplasia
  • Nonsurgical inter-vertebral disc disease
  • Degenerative myelopathy
  • Other joint and nerve diseases


Tramadol is sometimes also prescribed for relief of anxiety and even coughing.

Main Ingredient in Tramadol

Tramadol hydrochloride is the main active ingredient of Tramadol medications. It can be combined with other weaker or stronger analgesics to enhance the painkilling effect. Tramadol is like a mild version of morphine. It works by blocking chemicals in nerve pathways that signal the perception of pain. Norepinephrine and serotonin are the chemicals that stimulate feelings of happiness and well being. Tramadol blocks the reuptake of these two chemicals so that your dog will feel more of the happiness effect than the perception of pain.


This works only as a diversion that tricks your dog’s mind to perceive happiness rather than pain. Tramadol does not, however, help relieve any of the symptoms that cause the pain. Unlike NSAIDs (Non-steroidal anti-inflammatory drugs), Tramadol does not help reduce swelling and pain in the affected parts. It does not provide assistance to the body’s compensatory and rehabilitative processes that help the body recover from the cause of pain.

Dosage and Cost of Tramadol for Dogs

The dosage for Tramadol depends on the dog’s weight and condition. There is no dosage guide for Tramadol that the public may follow. It is strictly dispensed and administered per prescription only to prevent overdose. As a class 4 controlled substance, Tramadol cannot be bought and dosed like any over-the-counter drug. Only a licensed vet can determine the right dosage for your dog.


Tramadol for dogs is available in 50 mg tablets at pet pharmacies. The cost per tablet depends on the prescribed brand and also your location.


Tramdol 50 mg can cost between $0.75 and $2.00 per tablet.

Side Effects of Tramadol

Tramadol is a narcotic analgesic that causes your dog to feel at ease and happy to mask the pain. But it may also cause certain unwanted side effects.


Some of the common side effects your dog may experience while on medication include:

  • Changes in appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Anxiety
  • Dizziness
  • Drowsiness
  • Tremors


Aside from these side effects, you should also watch out for signs of overdose and adverse reactions that may cause serious problems in your dog:

  • Breathing difficulty
  • Decreased heart and pulse rate
  • Weakness and sleepiness
  • Excessive drooling
  • Excessive vomiting
  • Excessive tremors
  • Seizure
  • Loss of consciousness
  • Coma

These reactions can cause serious damage to your dog’s body. That is why Tramadol should be strictly given as prescribed.


In some cases though, even if you follow the vet’s directions religiously, it’s still possible for your dog to experience adverse reactions. This is because every dog is different. Many dogs can tolerate Tramadol well, but some dogs may not be able to put up with its effects.

Tramadol’s Interaction with Other Drugs

Tramadol is a strong painkiller that causes narcotic effects. These effects may interfere or counteract with the effects of other drugs. Tramadol should never be given to dogs who are also taking medications such as:

  • Selective serotonin re-uptake inhibitors (SSRIs)

Drugs like sertraline and fluoxetine are SSRIs that inhibit the re-uptake of serotonin in the body. If used with Tramadol, the effects might lead to overdose reactions.

  • Monoamine oxidase inhibitors (MAOIs)

Selegiline is a MAOI that inhibits the break-down of serotonin and norepinephrine. Using this with Tramadol will also lead to overdose effects.

Tramadol Alternatives

The risk of overdose and “addictiveness” to Tramadol is moderately high. That’s why many pet owners are advised to seek other safer options for their dog’s pain management.


Although it’s relatively safe to give Tramadol for acute pain, it isn’t the best medication for chronic pain. For dogs that need to take pain medications daily on a long-term basis, safer and more natural alternatives should be explored. One of the most popular alternatives to Tramadol is CBD oil.


CBD oil is a safe, naturally-derived supplement that can be given to your dog on a daily basis. It can be used an anti-inflammatory agent for pain management. You can also give CBD oil in different ways that your dog might enjoy.


CBD is an effective anti-inflammatory agent that helps the body to cope better and faster from pain and inflammation. It works by stimulating the endocannabinoid system (ECS) to control prostaglandin levels and establish chemical balance. This state of balance fights off inflammatory responses that cause pain and swelling in the affected parts.

Other safer alternatives also include:

  • Non-steroidal anti-inflammatory drugs (NSAIDs)

NSAIDs are also chemical drugs like Tramadol, but they provide more beneficial effects and fewer side effects. NSAIDs benefit the body by regulating inflammatory responses to reduce swelling and pain. Unlike Tramadol, NSAIDs are better tolerated and are not addictive and mind-clouding.

  • Physical therapy

Physical therapy will help your dog recover faster and manage pain better. The exercises in physical therapy will gradually build your dog’s physical vitality to restore normal functions and fight off inflammation.

  • Acupuncture

Acupuncture is also becoming popular for dogs with chronic pain. This procedure works by regulating the body’s energy flow so that pain can become more manageable.

  • Herbal therapy

There are some herbs than can be safely given to your dog for pain management like Turmeric. However, you must ask your vet first before giving any herbal medication because herbs work just like drugs. If you give the wrong herb for the wrong condition, it may cause bad reactions and worsen the problem.

It’s not bad to trust prescription drugs and to stick to them. There are prescriptions that cannot be alternated with anything else.

However, it’s every owner’s responsibility to look out and ahead for their dogs. If it’s possible to choose other safer options, you should always discuss them with your vet.






benadryl for dogs

Side Effects of Benadryl For Dogs & Alternatives

Benadryl for Dogs: Usage, Side Effects, and Other Concerns

The compulsion to head to our medicine cabinet to find something that could treat our dogs with can be strong, yet very dangerous. Due to their differences in anatomy, humans and dogs can react differently to the same medicine. This is why veterinarians caution dog owners against making an uninformed decision when treating their dogs.


Benadryl is one medicine that can be used for both humans and dogs. And while it is always a good idea for you to consult your veterinarian first, here are some facts that you should know about using Benadryl for dogs.

What Is Benadryl for Dogs?

Benadryl is the brand name for a substance known as diphenhydramine HCL. This drug can relieve many of the symptoms directly connected to allergies such as itching, sneezing, and rashes. For dogs, Benadryl is effective in reducing other symptoms of an allergy. These include:

  • Swelling and inflammation
  • Coughing
  • Runny eyes and nose
  • Anaphylactic reactions

Benadryl can also work as a sedative, which could help calm them. Some breeds are also mentally affected by an allergy that manifests through aggression and restlessness. It has also been used by veterinarians as a pre-treatment before introducing a vaccine to the animal.

Dosage of Benadryl

Like many other over-the-counter drugs, the dosage of Benadryl for dogs is dependent on the size and weight of that particular breed. As such, the standard for Benadryl application is 1 mg per pound of body weight. It should also be administered orally 2 to 3 times a day until the symptoms have stopped manifesting.


If the dog is already experiencing an acute allergic reaction, it is recommended that you skip the oral administration altogether and visit the vet. Some allergic conditions require a combination of medicine in order to be effectively addressed.

Side Effects of Benadryl

Benadryl can cause some effects to manifest on your dog, especially through repeated dosages. As a mild sedative, Benadryl can make your dog drowsy and lethargic for several hours. Other common side effects include drying in the mouth, excessive salivation, rapid breathing and increased heart rate, and urinary retention.


There also some rare side effects that any dog owner should be aware of if they apply the drug to their pets. Some dogs could experience changes in their appetite, depending on their breed. Others could experience diarrhea and would vomit profusely.


Also, Benadryl is known to cause some adverse reactions if the dog is experiencing any of the following conditions:

  • Bladder neck obstruction
  • Seizures
  • Allergic lung disease
  • Pregnancy
  • Angle closure glaucoma
  • Hypertension

Cost of Benadryl for Dogs

Benadryl is one of the cheaper over-the-counter drugs that you could purchase for dogs. The price for a capsule bottle that contains 500 to 1000 capsules can go in between $2.00 and $5.00 in drug stores and online suppliers.


Standard Benadryl tablets come in 25 mg units that is perfect for administering on average-sized dogs like Labradors and Collies. There is also a 50mg tablet that is advisable for larger and heavier dogs. For smaller dogs, it is best to coordinate the dosage with the veterinarian. This way, unpleasant side effects could be avoided.

Interactions with Other Drugs

Benadryl is known to react negatively if used in tandem with other medications. It reportedly has an addictive effect when combined with other sedatives, and other anticholinergic substances.


When used with medication that contains epinephrine, Benadryl is known to enhance the effects of the substance. As such, Benadryl is not to be used when treating allergic reactions for insect bites and stings if the dog already has taken an epinephrine-based tablet.


Lastly, Benadryl is known to lessen the effects of warfarin and heparin. If the dog is on medication for diseases like pancreatitis and laminitis or is recovering from burns, the use of Benadryl is not advised.


Due to this, it is highly recommended that you consult with a veterinarian before attempting to administer the medicine to your dog. They would know if introducing the drug would cause some interactions with other medications or worsen pre-existing conditions.


Ingredients in Benadryl

The primary ingredient in Benadryl is a substance known as Diphenhydramine HCI. This is an antihistamine. This means its primary purpose is to block receptors to prevent the buildup of histamines.


In essence, Diphenhydramine prevents the body to filter that substance without suffering the worst effects that an allergic reaction could bring. Aside from Diphenhydramine, Benadryl also contains other inactive ingredients.

  • Stearic acid
  • Pregelatinized starch
  • Microcrystalline cellulose
  • Hypermellose
  • Crospovidone
  • Colloidal silicone dioxide
  • Titanium oxide
  • Talc
  • Candellila wax

Alternatives to Benadryl for Dogs

Although Benadryl is highly recommended by veterinarians in treating canine allergic reactions, it is not the only option available out there. Here are some natural options that could serve as an alternative to Benadryl.

  1. Collostrum – Usually found in the milk of mothers, Colostrum is known to contain an ingredient called Praline-Rich Polypeptide. This substance targets the immune system and rewires its usual response to allergens.

It can also inhibit the cells that amplify allergic reactions and can create helper and suppressor T-Cells that will suppress the effects of allergic reactions.

  1. Mushrooms, Seaweed, and Yeast

These readily available ingredients contain a substance known as beta-glucan. The substance essentially changes the body’s response to allergies by energizing a kind of cell called a Macrophage.


This cell, in turn, traps and destroys foreign substances coursing through the body such as viruses and allergens. It also has an added benefit of keeping the dog active, unlike Benadryl, which sedates them.

  1. CBD Oil

An extract from the Cannabis plant, CBD oil contains cannabinoids that are reported to be effective against allergic dermatitis. Applied topically, CBD oil can help a dog deal with chronic itching and allergies, while also restoring the luster of the skin.


And the best part is that CBD oil is completely safe for dogs. Dogs that have been administered the oil have suffered nothing similar to what Benadryl brings, although they still do get drowsy after a few hours.


Due to this, CBD Oil can be considered a superior alternative to Benadryl tablets. If you are still nervous about using CBD oil for your dog, you can always consult with a veterinarian to address any concern about dosage and application.


back to home


Phenobarbital for dogs

Side Effects of Phenobarbital for Dogs & Alternative

What Is Phenobarbital?

Phenobarbital is a barbiturate. A type of depressant, barbiturates affect the central nervous system.  Phenobarbital is also known as Barbital or Luminal. It is used to control the severity and extent of seizures. It does this by lowering and balancing the activity of neurons in the dog’s brain.

Dog’s seizures can be caused by some underlying health problems such as toxin ingestion, brain tumor, head injury, kidney disease, anemia and liver shunt. If there is no underlying cause, the seizure is considered to be epilepsy.

The drug also decreases the Glutamate neurotransmitter. Glutamate is the one responsible for sending signals between nerve cells.

If the dog is experiencing seizures, remain calm. Try to calm the dog as well. This will prevent further problems such as brain trauma or brain cancer. Putting light pressure on the dog’s eyeball can decrease the duration of the seizure.

You should also record the severity and duration of the seizure. This will help the veterinarian evaluate the dog’s case better. The information recorded can also help the veterinarian calculate how much phenobarbital will be given to the dog.

Dogs prone to seizures are:

  • Beagle
  • Collie
  • Basset Hound
  • Belgian Tervuren
  • Golden Retriever
  • Keeshond
  • Schnauzer
  • Shetland Sheepdog
  • Cocker Spaniel
  • Labrador retriever

Phenobarbital Contraindications

The medication should not be given to dogs with the following conditions:

  • Respiratory Problems
  • Kidney Disease
  • Addison’s Disease
  • Liver Disease
  • Heart Disease
  • Anemia
  • Hypovolemia

Phenobarbital is a strong barbiturate that can alter the function of the dog’s organs. It can also affect the dog’s blood. It is wise to consult a veterinarian before giving any medications to your pet.

Phenobarbital Dosage

The dosage depends on the dog’s breed and weight. It also depends on the severity and frequency of the dog’s seizures.

Typically, the veterinarian will start a dose of 1-2 mg per pound of the dog’s body weight. Depending on the severity of the seizure, the dose can increase up to 8 mg per pound per day. The dose also depends on the dog’s response to the medication.

The medication is often given in doses measured in “grains” rather than milligrams. One grain is equivalent to about 60 milligrams. It is available in ¼ grain, ½ grain, 1 grain and 100 milligram tablets.

Injectable form of the medicine is also available. This comes in 65 and 130 milligram or milliliter doses.

The medication should be given every 12 hours. In case a dose was missed, never give two doses of the medication at once. This can result to nervous system depression, and even phenobarbital poisoning.

If you want to stop giving the medicine to your dog, do it gradually, and do it with the guidance of your veterinarian.

Phenobarbital Side Effects

If the dog is using the medicine for the first time, it will be groggy and wobbly. This will eventually disappear as the dog gets used to phenobarbital.

Other side effects of the medicine include:

  • Lethargy
  • Anxiety
  • Loss of Coordination
  • Increased Urination
  • Increased Thirst or Appetite
  • Weight Gain
  • Restlessness
  • Ataxia
  • Depression
  • Hyper excitability
  • Liver Damage – The side effect may be caused by long-term use of the medicine.

Signs of liver damage or liver failure include the following:

  • Vomiting
  • Diarrhea and changes in stool
  • Jaundice (yellow coloring of mucous membrane and skin)
  • Anorexia or loss of appetite

Phenobarbital Cost

Phenobarbital is commonly used to treat seizures in dogs because it is inexpensive. 15-16. 2 mg tablets cost around 1.32 dollars per tablet. 30- 32.4 milligram tablets cost around 1.48 dollars per tablet.

Phenobarbital Interaction with Other Drugs

Drugs that can strengthen the effect of phenobarbital include chlorambucil, griseofulvin and some antihistamines. It is not wise to combine these medicines as it will increase the effect of phenobarbital. This can damage the dog’s brain cells, and can also lead to overdose.

There are also drugs that interfere with phenobarbital. These drugs include beta-blockers, some steroids and metronidazole. Other medicines that do not work well with phenobarbital include Lysodren (used to treat Cushing syndrome), Theophylline (airway dilator) and cyclosporine (for immune mediated diseases).  These medicines make phenobarbital less effective. They can even worsen the frequency of seizures.

Some medicines help taper side effects of phenobarbital. These medicines help balance the effect so as not to damage other organs of the dog. These medicines include Potassium Bromide.

Phenobarbital Ingredients

The active ingredient is phenobarbital.

In 15 mg, 30 mg and 60 mg phenobarbital, the other ingredients are:

  • Calcium Stearate
  • Colloidal Silicon Dioxide
  • Corn Starch
  • Microcrystalline Cellulose

In 100 mg of phenobarbital, other ingredients are:

  • Anhydrous Lactose
  • Docusate Sodium
  • Colloidal Silicone Dioxide
  • Magnesium Stearate
  • Lactose Monohydrate
  • Sodium Starch Glycolate
  • Microcrystalline Cellulose

Phenobarbital Alternatives

Phenobarbital is an effective medicine to help treat seizures, but it has strong side effects. There are other medicines that have lesser side effects than phenobarbital.

Diazepam, commonly known as Valium, is an anti-convulsant drug. It helps reduce the neuron’s activity.

Levetiracetam, also known as Keppra, is an anticonvulsant drug. It has a lower dosage of phenobarbital. This means it has lesser adverse effects.

Zonisamide or Zonegran is a new anti-seizure drug for dogs. The starting dose is higher than phenobarbital, but it has lesser side effects.

Changes in the dog’s diet can help reduce seizures. A ketogenic diet is advised by veterinarians. The diet is high in fats and low in carbohydrates.

Acupuncture is also a way to reduce the frequency and severity of seizures. This works best with strict consistency.

One safe and effective alternative to phenobarbital is CBD oil. CBD oil stands for Cannabidiol. CBD oil is extracted from the marijuana plant. The oil has an impact on the nervous system and brain.

CBD oil is used to treat cancer, seizures, pain and other diseases in dogs. It is an effective medicine to use in seizures. This is because it interacts with the endocannabinoid receptors in the dog’s body.

The two types of these receptors are:

  • CBD2 receptors- receptors primarily located in the immune system
  • CBD 1 receptors- receptors centralized in the nervous system and brain

CBD oil helps reduce seizure by calming the neurons that fire up during seizures. The only side effect that can be experienced by the dog is mild drowsiness.


back to home

Galliprant For dogs

Galliprant for Dogs Side Effects & Galliprant Alternatives

Side Effects of Galliprant for Dogs & Alternatives

Osteoarthritis is a joint condition where bones rub against each other. The protective tissue between the bones, called the cartilage, can wear out over time. This can cause pain and inflammation to the affected joint.

It can be painful enough to make your pet less active. Simple tasks like walking can be hard for them. It can also affect their rest and sleep.

Osteoarthritis prevents your dog from moving. If your dog does not move much, it can cause more joint pain. Thus, this condition can be a painful cycle.

This condition is usually present in older dogs. Yet, some obese dogs can also be at risk, since their extra weight can strain their joints. What are the signs of osteoarthritis in dogs?

  • They are reluctant to walk.
  • You notice stiffness when they lie down or getting up.
  • They avoid walking on the stairs.
  • Your dog is spending more time sleeping.
  • They whine or act in pain, especially when changing positions.

What Is Galliprant for Dogs?

Galliprant is a veterinary drug used for dogs. Vets can give it to dogs with mild to moderate osteoarthritis. It controls the pain and inflammation associated with the condition.

You can get this drug via a prescription. It comes in tablet form, and taken once a day.

The appropriate dose depends on your dog’s weight. The amount of treatment will depend on your dog’s improvement.

Dogs at least 9 months and 8 pounds can take Galliprant. It is not advisable to give Galliprant to younger and smaller dogs since it can cause unwanted effects.

Galliprant lessens the side effect on the kidneys, liver, and gastrointestinal system. Organ damage is common when using anti-inflammatory drugs in the long run.

Dosage of Galliprant

This drug is available in 20 mg, 60 mg, and 100 mg tablets. A dose of 0.9 mg per pound of body weight (0.9 mg/lb or 2 mg/kg) is enough for a day.

It would be safe to inform your vet if your dog is pregnant, lactating, or has a history of heart disease. Inform your vet if your dog is taking other anti-inflammatory drugs.

Take note of any previous allergies and digestive issues (such as diarrhea, bloody stools, or decreased appetite) before giving it to your dog.

You can give it to your dog with an empty stomach at least an hour before a meal.

Side Effects of Galliprant

The most common reported side effects from using the drug are vomiting and diarrhea. It can also decrease the dog’s appetite. Some owners said that it made their pet easily tired.

Mild vomiting symptoms may also be experienced, but it often goes away over time. Galliprant does not affect the behavior or personality of the dog.

Ulcer and anemia are also possible. Do not give Galliprant to dogs with Grapiprant sensitivity. If you notice these signs, you should inform your veterinarian right away.

Cost of Galliprant

The price of Galliprant starts from $38.99. It is comparable to Rimadyl. It has a generic name of Novox Carprofen.

Rimadyl is a common non-steroidal and anti-inflammatory medication. It can also reduce pain in dogs.

Interaction with Other Drugs

This drug can interact with other non-steroidal anti-inflammatory drugs. It can also interact with corticosteroids. Some common examples of these drugs are Aspirin, as well as Carprofen, Meloxicam, and Prednisone.

Ingredients in Galliprant

The active ingredient present in Galliprant is Grapipant. It is a non-steroidal and anti-inflammatory drug in the piprant class.

Grapiprant antagonizes prostaglandin receptors to reduce pain and inflammation. It is only administered to dogs.

Galliprant Alternatives

  • Rimadyl –  Rimadyl is a non-steroidal anti-inflammatory drug used for the treatment of osteoarthritis. It is also prescribed for other joint diseases like hip dysplasia.

The drug can also help during fever. It can even reduce pain from surgery and dental procedures.

Rimadyl is a common drug prescribed by vets. Yet, liver and kidney complications sometimes occur with long term use. It is advisable to do blood work to make sure these side effects do not appear.

  • CBD Oil –  One of the best alternatives for osteoarthritis treatment in dogs is CBD oil. Cannabidiol has incredible benefits. It is a natural compound that offers a wide range of use.

CBD oil has the same benefits of medical marijuana with no psychoactive effects. It works with the endocannabinoid system of the body. This system releases the compound present in CBD oil to heal the entire body.

These compounds present in CBD oil target the problem areas; thus, treating the dog’s ailments. It targets the cause of pain and inflammation in a natural process.


Why CBD Oil Is Good for Osteoarthritis


One of the amazing properties of using CBD oil is reducing inflammation. By reducing inflammation, the pain will lessen, too. This can encourage your dog to move more.

Getting your dog active can loosen their joints. This can promote healing. Having enough activity can also help them to lose weight.

CBD oil in dogs can also help to improve their digestion. It increases their appetite and gives them the energy they need for their physical activities.

The problem with giving your dog traditional anti-inflammatory medicines are the side effects. These pharmaceutical medicines can cause problems such as:

  • Incontinence, loose stools, or diarrhea.
  • Your dog can be clumsy with a lack of awareness.
  • Allergies and other skin problems.
  • Gastrointestinal ulcers.
  • Vomiting, weight loss and lack of appetite.
  • Liver and other organ damage.

CBD oil is a natural way of treating osteoarthritis in dogs. There is no exact dosage for CBD oil. Try to start small and increase the dosage if needed.

Another benefit of using CBD oil for dogs is reducing anxiety. It can also relieve stress and gastrointestinal issues.

It helps to fight and prevent cancer while managing its symptoms. CBD oil helps the immune system by killing cancer cells to prevent further growth.

CBD oil is an effective treatment that does not damage the kidneys, liver, and other organs. Since it is an organic compound, the side effects are minimal to none.

Osteoarthritis is a degenerative disease, but it is manageable. With proper care and treatment, your dog can live a happy, healthy, and fulfilled life.


Galliprant—A Nonsteroidal Anti-Inflammatory Drug (NSAID) for Dogs with Osteoarthritis

European Medicines Agency – Galliprant

1-800-PetMeds – Galliprant

Side Effects of Galliprant

Galliprant New Arthritis Medication for Dogs

Committee for Medicinal Products for Veterinary Use

Should you use CBD oil for dog’s arthritis?

How CBD Oil for Arthritis in Dogs Works

Cannabis Oil for Dogs: Everything You Need to Know

back to home