Medicine

tramadol for dogs side effects alternatives

Tramadol For Dogs Side Effects Tramadol & Alternatives

Side Effects of Tramadol For Dogs & Alternatives

It can be flustering not to know what to do when your dog needs your help, especially when they’re down with pain. The most automatic response is to go to the vet and, without any question, buy whatever painkiller is in the prescription. Following the prescription strictly is not unwise. However, it’s better to think about your dog’s medication more extensively before settling with a painkiller. This is most important if your dog is suffering from chronic pain.

One of the painkillers you should think twice about is Tramadol. Though Tramadol can give your dog fast-acting and long-lasting relief, it isn’t formulated to be safe for long-term use. In the following post, you’ll learn all about Tramadol and why you should be cautious in giving them to your dogs.

What Is Tramadol for Dogs?

Tramadol is the generic name for a kind of opioid drug. It is medically used as a narcotic analgesic for relieving moderate to severe pain in both humans and dogs.

This kind of painkiller can be prescribed for dogs who are suffering from acute and chronic pain caused by any of the following conditions:

  • Post-operative pain
  • Physical injury
  • Cancer symptoms
  • Osteoarthritis
  • Hip dysplasia
  • Nonsurgical inter-vertebral disc disease
  • Degenerative myelopathy
  • Other joint and nerve diseases

 

Tramadol is sometimes also prescribed for relief of anxiety and even coughing.

Main Ingredient in Tramadol

Tramadol hydrochloride is the main active ingredient of Tramadol medications. It can be combined with other weaker or stronger analgesics to enhance the painkilling effect. Tramadol is like a mild version of morphine. It works by blocking chemicals in nerve pathways that signal the perception of pain. Norepinephrine and serotonin are the chemicals that stimulate feelings of happiness and well being. Tramadol blocks the reuptake of these two chemicals so that your dog will feel more of the happiness effect than the perception of pain.

 

This works only as a diversion that tricks your dog’s mind to perceive happiness rather than pain. Tramadol does not, however, help relieve any of the symptoms that cause the pain. Unlike NSAIDs (Non-steroidal anti-inflammatory drugs), Tramadol does not help reduce swelling and pain in the affected parts. It does not provide assistance to the body’s compensatory and rehabilitative processes that help the body recover from the cause of pain.

Dosage and Cost of Tramadol for Dogs

The dosage for Tramadol depends on the dog’s weight and condition. There is no dosage guide for Tramadol that the public may follow. It is strictly dispensed and administered per prescription only to prevent overdose. As a class 4 controlled substance, Tramadol cannot be bought and dosed like any over-the-counter drug. Only a licensed vet can determine the right dosage for your dog.

 

Tramadol for dogs is available in 50 mg tablets at pet pharmacies. The cost per tablet depends on the prescribed brand and also your location.

 

Tramdol 50 mg can cost between $0.75 and $2.00 per tablet.

Side Effects of Tramadol

Tramadol is a narcotic analgesic that causes your dog to feel at ease and happy to mask the pain. But it may also cause certain unwanted side effects.

 

Some of the common side effects your dog may experience while on medication include:

  • Changes in appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Anxiety
  • Dizziness
  • Drowsiness
  • Tremors

 

Aside from these side effects, you should also watch out for signs of overdose and adverse reactions that may cause serious problems in your dog:

  • Breathing difficulty
  • Decreased heart and pulse rate
  • Weakness and sleepiness
  • Excessive drooling
  • Excessive vomiting
  • Excessive tremors
  • Seizure
  • Loss of consciousness
  • Coma

These reactions can cause serious damage to your dog’s body. That is why Tramadol should be strictly given as prescribed.

 

In some cases though, even if you follow the vet’s directions religiously, it’s still possible for your dog to experience adverse reactions. This is because every dog is different. Many dogs can tolerate Tramadol well, but some dogs may not be able to put up with its effects.

Tramadol’s Interaction with Other Drugs

Tramadol is a strong painkiller that causes narcotic effects. These effects may interfere or counteract with the effects of other drugs. Tramadol should never be given to dogs who are also taking medications such as:

  • Selective serotonin re-uptake inhibitors (SSRIs)

Drugs like sertraline and fluoxetine are SSRIs that inhibit the re-uptake of serotonin in the body. If used with Tramadol, the effects might lead to overdose reactions.

  • Monoamine oxidase inhibitors (MAOIs)

Selegiline is a MAOI that inhibits the break-down of serotonin and norepinephrine. Using this with Tramadol will also lead to overdose effects.

Tramadol Alternatives

The risk of overdose and “addictiveness” to Tramadol is moderately high. That’s why many pet owners are advised to seek other safer options for their dog’s pain management.

 

Although it’s relatively safe to give Tramadol for acute pain, it isn’t the best medication for chronic pain. For dogs that need to take pain medications daily on a long-term basis, safer and more natural alternatives should be explored. One of the most popular alternatives to Tramadol is CBD oil.

 

CBD oil is a safe, naturally-derived supplement that can be given to your dog on a daily basis. It can be used an anti-inflammatory agent for pain management. You can also give CBD oil in different ways that your dog might enjoy.

 

CBD is an effective anti-inflammatory agent that helps the body to cope better and faster from pain and inflammation. It works by stimulating the endocannabinoid system (ECS) to control prostaglandin levels and establish chemical balance. This state of balance fights off inflammatory responses that cause pain and swelling in the affected parts.

Other safer alternatives also include:

  • Non-steroidal anti-inflammatory drugs (NSAIDs)

NSAIDs are also chemical drugs like Tramadol, but they provide more beneficial effects and fewer side effects. NSAIDs benefit the body by regulating inflammatory responses to reduce swelling and pain. Unlike Tramadol, NSAIDs are better tolerated and are not addictive and mind-clouding.

  • Physical therapy

Physical therapy will help your dog recover faster and manage pain better. The exercises in physical therapy will gradually build your dog’s physical vitality to restore normal functions and fight off inflammation.

  • Acupuncture

Acupuncture is also becoming popular for dogs with chronic pain. This procedure works by regulating the body’s energy flow so that pain can become more manageable.

  • Herbal therapy

There are some herbs than can be safely given to your dog for pain management like Turmeric. However, you must ask your vet first before giving any herbal medication because herbs work just like drugs. If you give the wrong herb for the wrong condition, it may cause bad reactions and worsen the problem.

It’s not bad to trust prescription drugs and to stick to them. There are prescriptions that cannot be alternated with anything else.

However, it’s every owner’s responsibility to look out and ahead for their dogs. If it’s possible to choose other safer options, you should always discuss them with your vet.

 

References:

 

  1. https://www.akc.org/expert-advice/health/tramadol-for-dogs/
  2. https://www.honestpaws.com/blogs/medication/tramadol-for-dogs
  3. https://dogtime.com/dog-health/59541-tramadol-dogs-uses-dosage-side-effects
  4. https://www.care.com/c/stories/6487/tramadol-for-dogs-uses-side-effects-and-alternative-treatment-options/
  5. https://www.1800petmeds.com/Tramadol-prod11064.html
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benadryl for dogs side effects and alternatives

Benadryl For Dogs Side Effects & Benadryl Alternatives

Benadryl for Dogs: Usage, Side Effects, and Other Concerns

The compulsion to head to our medicine cabinet to find something that could treat our dogs with can be strong, yet very dangerous. Due to their differences in anatomy, humans and dogs can react differently to the same medicine. This is why veterinarians caution dog owners against making an uninformed decision when treating their dogs.

 

Benadryl is one medicine that can be used for both humans and dogs. And while it is always a good idea for you to consult your veterinarian first, here are some facts that you should know about using Benadryl for dogs.

What Is Benadryl for Dogs?

Benadryl is the brand name for a substance known as diphenhydramine HCL. This drug can relieve many of the symptoms directly connected to allergies such as itching, sneezing, and rashes. For dogs, Benadryl is effective in reducing other symptoms of an allergy. These include:

  • Swelling and inflammation
  • Coughing
  • Runny eyes and nose
  • Anaphylactic reactions

Benadryl can also work as a sedative, which could help calm them. Some breeds are also mentally affected by an allergy that manifests through aggression and restlessness. It has also been used by veterinarians as a pre-treatment before introducing a vaccine to the animal.

Dosage of Benadryl

Like many other over-the-counter drugs, the dosage of Benadryl for dogs is dependent on the size and weight of that particular breed. As such, the standard for Benadryl application is 1 mg per pound of body weight. It should also be administered orally 2 to 3 times a day until the symptoms have stopped manifesting.

 

If the dog is already experiencing an acute allergic reaction, it is recommended that you skip the oral administration altogether and visit the vet. Some allergic conditions require a combination of medicine in order to be effectively addressed.

Side Effects of Benadryl

Benadryl can cause some effects to manifest on your dog, especially through repeated dosages. As a mild sedative, Benadryl can make your dog drowsy and lethargic for several hours. Other common side effects include drying in the mouth, excessive salivation, rapid breathing and increased heart rate, and urinary retention.

 

There also some rare side effects that any dog owner should be aware of if they apply the drug to their pets. Some dogs could experience changes in their appetite, depending on their breed. Others could experience diarrhea and would vomit profusely.

 

Also, Benadryl is known to cause some adverse reactions if the dog is experiencing any of the following conditions:

  • Bladder neck obstruction
  • Seizures
  • Allergic lung disease
  • Pregnancy
  • Angle closure glaucoma
  • Hypertension

Cost of Benadryl for Dogs

Benadryl is one of the cheaper over-the-counter drugs that you could purchase for dogs. The price for a capsule bottle that contains 500 to 1000 capsules can go in between $2.00 and $5.00 in drug stores and online suppliers.

 

Standard Benadryl tablets come in 25 mg units that is perfect for administering on average-sized dogs like Labradors and Collies. There is also a 50mg tablet that is advisable for larger and heavier dogs. For smaller dogs, it is best to coordinate the dosage with the veterinarian. This way, unpleasant side effects could be avoided.

Interactions with Other Drugs

Benadryl is known to react negatively if used in tandem with other medications. It reportedly has an addictive effect when combined with other sedatives, and other anticholinergic substances.

 

When used with medication that contains epinephrine, Benadryl is known to enhance the effects of the substance. As such, Benadryl is not to be used when treating allergic reactions for insect bites and stings if the dog already has taken an epinephrine-based tablet.

 

Lastly, Benadryl is known to lessen the effects of warfarin and heparin. If the dog is on medication for diseases like pancreatitis and laminitis or is recovering from burns, the use of Benadryl is not advised.

 

Due to this, it is highly recommended that you consult with a veterinarian before attempting to administer the medicine to your dog. They would know if introducing the drug would cause some interactions with other medications or worsen pre-existing conditions.

 

Ingredients in Benadryl

The primary ingredient in Benadryl is a substance known as Diphenhydramine HCI. This is an antihistamine. This means its primary purpose is to block receptors to prevent the buildup of histamines.

 

In essence, Diphenhydramine prevents the body to filter that substance without suffering the worst effects that an allergic reaction could bring. Aside from Diphenhydramine, Benadryl also contains other inactive ingredients.

  • Stearic acid
  • Pregelatinized starch
  • Microcrystalline cellulose
  • Hypermellose
  • Crospovidone
  • Colloidal silicone dioxide
  • Titanium oxide
  • Talc
  • Candellila wax

Alternatives to Benadryl for Dogs

Although Benadryl is highly recommended by veterinarians in treating canine allergic reactions, it is not the only option available out there. Here are some natural options that could serve as an alternative to Benadryl.

  1. Collostrum – Usually found in the milk of mothers, Colostrum is known to contain an ingredient called Praline-Rich Polypeptide. This substance targets the immune system and rewires its usual response to allergens.

It can also inhibit the cells that amplify allergic reactions and can create helper and suppressor T-Cells that will suppress the effects of allergic reactions.

  1. Mushrooms, Seaweed, and Yeast

These readily available ingredients contain a substance known as beta-glucan. The substance essentially changes the body’s response to allergies by energizing a kind of cell called a Macrophage.

 

This cell, in turn, traps and destroys foreign substances coursing through the body such as viruses and allergens. It also has an added benefit of keeping the dog active, unlike Benadryl, which sedates them.

  1. CBD Oil

An extract from the Cannabis plant, CBD oil contains cannabinoids that are reported to be effective against allergic dermatitis. Applied topically, CBD oil can help a dog deal with chronic itching and allergies, while also restoring the luster of the skin.

 

And the best part is that CBD oil is completely safe for dogs. Dogs that have been administered the oil have suffered nothing similar to what Benadryl brings, although they still do get drowsy after a few hours.

 

Due to this, CBD Oil can be considered a superior alternative to Benadryl tablets. If you are still nervous about using CBD oil for your dog, you can always consult with a veterinarian to address any concern about dosage and application.

References:

https://www.healthline.com/health/anticholinergics

https://www.petcarerx.com/diphenhydramine-50mg/11556

https://www.petmd.com/dog/care/can-i-give-my-dog-benadryl-and-if-so-how-much

https://www.akc.org/expert-advice/health/benadryl-for-dogs/

https://www.wedgewoodpetrx.com/learning-center/professional-monographs/diphenhydramine-for-veterinary-use.html

https://www.rxlist.com/benadryl-drug.htm#indications

https://www.dogsnaturallymagazine.com/allergy-relief-for-dogs-top-ten-remedies/

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Phenobarbital for dogs side effects and alternatives

Phenobarbital for Dogs Side Effects & Phenobarbital Alternative

What Is Phenobarbital?

Phenobarbital is a barbiturate. A type of depressant, barbiturates affect the central nervous system.  Phenobarbital is also known as Barbital or Luminal. It is used to control the severity and extent of seizures. It does this by lowering and balancing the activity of neurons in the dog’s brain.

Dog’s seizures can be caused by some underlying health problems such as toxin ingestion, brain tumor, head injury, kidney disease, anemia and liver shunt. If there is no underlying cause, the seizure is considered to be epilepsy.

The drug also decreases the Glutamate neurotransmitter. Glutamate is the one responsible for sending signals between nerve cells.

If the dog is experiencing seizures, remain calm. Try to calm the dog as well. This will prevent further problems such as brain trauma or brain cancer. Putting light pressure on the dog’s eyeball can decrease the duration of the seizure.

You should also record the severity and duration of the seizure. This will help the veterinarian evaluate the dog’s case better. The information recorded can also help the veterinarian calculate how much phenobarbital will be given to the dog.

Dogs prone to seizures are:

  • Beagle
  • Collie
  • Basset Hound
  • Belgian Tervuren
  • Golden Retriever
  • Keeshond
  • Schnauzer
  • Shetland Sheepdog
  • Cocker Spaniel
  • Labrador retriever

Phenobarbital Contraindications

The medication should not be given to dogs with the following conditions:

  • Respiratory Problems
  • Kidney Disease
  • Addison’s Disease
  • Liver Disease
  • Heart Disease
  • Anemia
  • Hypovolemia

Phenobarbital is a strong barbiturate that can alter the function of the dog’s organs. It can also affect the dog’s blood. It is wise to consult a veterinarian before giving any medications to your pet.

Phenobarbital Dosage

The dosage depends on the dog’s breed and weight. It also depends on the severity and frequency of the dog’s seizures.

Typically, the veterinarian will start a dose of 1-2 mg per pound of the dog’s body weight. Depending on the severity of the seizure, the dose can increase up to 8 mg per pound per day. The dose also depends on the dog’s response to the medication.

The medication is often given in doses measured in “grains” rather than milligrams. One grain is equivalent to about 60 milligrams. It is available in ¼ grain, ½ grain, 1 grain and 100 milligram tablets.

Injectable form of the medicine is also available. This comes in 65 and 130 milligram or milliliter doses.

The medication should be given every 12 hours. In case a dose was missed, never give two doses of the medication at once. This can result to nervous system depression, and even phenobarbital poisoning.

If you want to stop giving the medicine to your dog, do it gradually, and do it with the guidance of your veterinarian.

Phenobarbital Side Effects

If the dog is using the medicine for the first time, it will be groggy and wobbly. This will eventually disappear as the dog gets used to phenobarbital.

Other side effects of the medicine include:

  • Lethargy
  • Anxiety
  • Loss of Coordination
  • Increased Urination
  • Increased Thirst or Appetite
  • Weight Gain
  • Restlessness
  • Ataxia
  • Depression
  • Hyper excitability
  • Liver Damage – The side effect may be caused by long-term use of the medicine.

Signs of liver damage or liver failure include the following:

  • Vomiting
  • Diarrhea and changes in stool
  • Jaundice (yellow coloring of mucous membrane and skin)
  • Anorexia or loss of appetite

Phenobarbital Cost

Phenobarbital is commonly used to treat seizures in dogs because it is inexpensive. 15-16. 2 mg tablets cost around 1.32 dollars per tablet. 30- 32.4 milligram tablets cost around 1.48 dollars per tablet.

Phenobarbital Interaction with Other Drugs

Drugs that can strengthen the effect of phenobarbital include chlorambucil, griseofulvin and some antihistamines. It is not wise to combine these medicines as it will increase the effect of phenobarbital. This can damage the dog’s brain cells, and can also lead to overdose.

There are also drugs that interfere with phenobarbital. These drugs include beta-blockers, some steroids and metronidazole. Other medicines that do not work well with phenobarbital include Lysodren (used to treat Cushing syndrome), Theophylline (airway dilator) and cyclosporine (for immune mediated diseases).  These medicines make phenobarbital less effective. They can even worsen the frequency of seizures.

Some medicines help taper side effects of phenobarbital. These medicines help balance the effect so as not to damage other organs of the dog. These medicines include Potassium Bromide.

Phenobarbital Ingredients

The active ingredient is phenobarbital.

In 15 mg, 30 mg and 60 mg phenobarbital, the other ingredients are:

  • Calcium Stearate
  • Colloidal Silicon Dioxide
  • Corn Starch
  • Microcrystalline Cellulose

In 100 mg of phenobarbital, other ingredients are:

  • Anhydrous Lactose
  • Docusate Sodium
  • Colloidal Silicone Dioxide
  • Magnesium Stearate
  • Lactose Monohydrate
  • Sodium Starch Glycolate
  • Microcrystalline Cellulose

Phenobarbital Alternatives

Phenobarbital is an effective medicine to help treat seizures, but it has strong side effects. There are other medicines that have lesser side effects than phenobarbital.

Diazepam, commonly known as Valium, is an anti-convulsant drug. It helps reduce the neuron’s activity.

Levetiracetam, also known as Keppra, is an anticonvulsant drug. It has a lower dosage of phenobarbital. This means it has lesser adverse effects.

Zonisamide or Zonegran is a new anti-seizure drug for dogs. The starting dose is higher than phenobarbital, but it has lesser side effects.

Changes in the dog’s diet can help reduce seizures. A ketogenic diet is advised by veterinarians. The diet is high in fats and low in carbohydrates.

Acupuncture is also a way to reduce the frequency and severity of seizures. This works best with strict consistency.

One safe and effective alternative to phenobarbital is CBD oil. CBD oil stands for Cannabidiol. CBD oil is extracted from the marijuana plant. The oil has an impact on the nervous system and brain.

CBD oil is used to treat cancer, seizures, pain and other diseases in dogs. It is an effective medicine to use in seizures. This is because it interacts with the endocannabinoid receptors in the dog’s body.

The two types of these receptors are:

  • CBD2 receptors- receptors primarily located in the immune system
  • CBD 1 receptors- receptors centralized in the nervous system and brain

CBD oil helps reduce seizure by calming the neurons that fire up during seizures. The only side effect that can be experienced by the dog is mild drowsiness.

References

https://www.ncbi.nlm.nih.gov/pubmed/18426493

https://medlineplus.gov/druginfo/meds/a682007.html
https://www.webmd.com/drugs/2/drug-8689/phenobarbital-oral/details

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Galliprant For dogs side effects and alternatives

Galliprant for Dogs Side Effects & Galliprant Alternatives

Side Effects of Galliprant for Dogs & Alternatives

Osteoarthritis is a joint condition where bones rub against each other. The protective tissue between the bones, called the cartilage, can wear out over time. This can cause pain and inflammation to the affected joint.

It can be painful enough to make your pet less active. Simple tasks like walking can be hard for them. It can also affect their rest and sleep.

Osteoarthritis prevents your dog from moving. If your dog does not move much, it can cause more joint pain. Thus, this condition can be a painful cycle.

This condition is usually present in older dogs. Yet, some obese dogs can also be at risk, since their extra weight can strain their joints. What are the signs of osteoarthritis in dogs?

  • They are reluctant to walk.
  • You notice stiffness when they lie down or getting up.
  • They avoid walking on the stairs.
  • Your dog is spending more time sleeping.
  • They whine or act in pain, especially when changing positions.

What Is Galliprant for Dogs?

Galliprant is a veterinary drug used for dogs. Vets can give it to dogs with mild to moderate osteoarthritis. It controls the pain and inflammation associated with the condition.

You can get this drug via a prescription. It comes in tablet form, and taken once a day.

The appropriate dose depends on your dog’s weight. The amount of treatment will depend on your dog’s improvement.

Dogs at least 9 months and 8 pounds can take Galliprant. It is not advisable to give Galliprant to younger and smaller dogs since it can cause unwanted effects.

Galliprant lessens the side effect on the kidneys, liver, and gastrointestinal system. Organ damage is common when using anti-inflammatory drugs in the long run.

Dosage of Galliprant

This drug is available in 20 mg, 60 mg, and 100 mg tablets. A dose of 0.9 mg per pound of body weight (0.9 mg/lb or 2 mg/kg) is enough for a day.

It would be safe to inform your vet if your dog is pregnant, lactating, or has a history of heart disease. Inform your vet if your dog is taking other anti-inflammatory drugs.

Take note of any previous allergies and digestive issues (such as diarrhea, bloody stools, or decreased appetite) before giving it to your dog.

You can give it to your dog with an empty stomach at least an hour before a meal.

Side Effects of Galliprant

The most common reported side effects from using the drug are vomiting and diarrhea. It can also decrease the dog’s appetite. Some owners said that it made their pet easily tired.

Mild vomiting symptoms may also be experienced, but it often goes away over time. Galliprant does not affect the behavior or personality of the dog.

Ulcer and anemia are also possible. Do not give Galliprant to dogs with Grapiprant sensitivity. If you notice these signs, you should inform your veterinarian right away.

Cost of Galliprant

The price of Galliprant starts from $38.99. It is comparable to Rimadyl. It has a generic name of Novox Carprofen.

Rimadyl is a common non-steroidal and anti-inflammatory medication. It can also reduce pain in dogs.

Interaction with Other Drugs

This drug can interact with other non-steroidal anti-inflammatory drugs. It can also interact with corticosteroids. Some common examples of these drugs are Aspirin, as well as Carprofen, Meloxicam, and Prednisone.

Ingredients in Galliprant

The active ingredient present in Galliprant is Grapipant. It is a non-steroidal and anti-inflammatory drug in the piprant class.

Grapiprant antagonizes prostaglandin receptors to reduce pain and inflammation. It is only administered to dogs.

Galliprant Alternatives

  • Rimadyl –  Rimadyl is a non-steroidal anti-inflammatory drug used for the treatment of osteoarthritis. It is also prescribed for other joint diseases like hip dysplasia.

The drug can also help during fever. It can even reduce pain from surgery and dental procedures.

Rimadyl is a common drug prescribed by vets. Yet, liver and kidney complications sometimes occur with long term use. It is advisable to do blood work to make sure these side effects do not appear.

  • CBD Oil –  One of the best alternatives for osteoarthritis treatment in dogs is CBD oil. Cannabidiol has incredible benefits. It is a natural compound that offers a wide range of use.

CBD oil has the same benefits of medical marijuana with no psychoactive effects. It works with the endocannabinoid system of the body. This system releases the compound present in CBD oil to heal the entire body.

These compounds present in CBD oil target the problem areas; thus, treating the dog’s ailments. It targets the cause of pain and inflammation in a natural process.

 

Why CBD Oil Is Good for Osteoarthritis

 

One of the amazing properties of using CBD oil is reducing inflammation. By reducing inflammation, the pain will lessen, too. This can encourage your dog to move more.

Getting your dog active can loosen their joints. This can promote healing. Having enough activity can also help them to lose weight.

CBD oil in dogs can also help to improve their digestion. It increases their appetite and gives them the energy they need for their physical activities.

The problem with giving your dog traditional anti-inflammatory medicines are the side effects. These pharmaceutical medicines can cause problems such as:

  • Incontinence, loose stools, or diarrhea.
  • Your dog can be clumsy with a lack of awareness.
  • Allergies and other skin problems.
  • Gastrointestinal ulcers.
  • Vomiting, weight loss and lack of appetite.
  • Liver and other organ damage.

CBD oil is a natural way of treating osteoarthritis in dogs. There is no exact dosage for CBD oil. Try to start small and increase the dosage if needed.

Another benefit of using CBD oil for dogs is reducing anxiety. It can also relieve stress and gastrointestinal issues.

It helps to fight and prevent cancer while managing its symptoms. CBD oil helps the immune system by killing cancer cells to prevent further growth.

CBD oil is an effective treatment that does not damage the kidneys, liver, and other organs. Since it is an organic compound, the side effects are minimal to none.

Osteoarthritis is a degenerative disease, but it is manageable. With proper care and treatment, your dog can live a happy, healthy, and fulfilled life.

References:

Galliprant—A Nonsteroidal Anti-Inflammatory Drug (NSAID) for Dogs with Osteoarthritis

https://www.fda.gov/animal-veterinary/animal-health-literacy/galliprant-nonsteroidal-anti-inflammatory-drug-nsaid-dogs-osteoarthritis

European Medicines Agency – Galliprant

https://www.ema.europa.eu/en/documents/overview/galliprant-epar-summary-public_en.pdf

1-800-PetMeds – Galliprant

https://www.1800petmeds.com/Galliprant-prod110001.html

Side Effects of Galliprant

https://www.galliprantfordogs.com/about-galliprant/side-effects

Galliprant New Arthritis Medication for Dogs

https://bothellveterinarian.wordpress.com/2017/04/02/galliprant-new-arthritis-medication-for-dogs/

Committee for Medicinal Products for Veterinary Use

https://www.ema.europa.eu/en/documents/assessment-report/galliprant-epar-public-assessment-report_en.pdf

Should you use CBD oil for dog’s arthritis?

https://sitstay.com/blogs/good-dog-blog/cbd-oil-for-dogs-arthritis

How CBD Oil for Arthritis in Dogs Works

https://www.fomobones.com/blog/how-cbd-oil-for-arthritis-in-dogs-works/

Cannabis Oil for Dogs: Everything You Need to Know

https://www.petmd.com/dog/general-health/cannabis-oil-dogs-everything-you-need-know

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Banamine for dogs side effects and alternatives

Banamine For Dogs Side Effects & Banamine Alternatives

Banamine for Dogs: Is it Safe?

It is not only humans who suffer from arthritis and other related conditions; even dogs experience musculoskeletal disorders, too. When arthritis is untreated, it could keep your pet in pain and discomfort. For this reason, vets usually prescribe Banamine to reduce pain, inflammation, and fever. But, due to certain complications, using Banamine comes with many risks.

What Is Banamine for Dogs

Banamine, also known as Flunixin, is a non-steroidal anti-inflammatory drug that is used to treat pain and inflammation of muscles and joints in animals. Although the drug is primarily registered for horse and cattle use, it is also given to dogs and cats suffering from arthritis.

Banamine is also given to dogs that have undergone surgery, and are experiencing pain from surgical procedure. When a dog is in shock, the vet usually gives it for pain relief treatment.

Vets have reason to administer Banamine despite the move being risky. It can reduce fever, especially when the dog does not eat or drink. It also provides good pain control in the belly and eye areas. However, the pain relief is temporary. Vets administer Banamine through the mouth and not intravenously.

Dosage of Banamine

The usual dosage given to feverish dogs is 1 mg per kg of body weight, once a day, and no more than 3 days. This is because dogs are sensitive to the toxic ingredients present in Banamine.

Banamine is considered more potent than other non-steroidal and anti-inflammatory drugs for animals. It instantly reduces lameness and swelling joints in dogs as well as in other affected animals.

Side Effects of Banamine

Banamine is generally safe. That is why vets still administer it. However, frequent use can lead to several side effects.

The drug should not be given to dogs with kidney, heart, liver, or blood disease. It should also not be administered to animals with gastrointestinal issues and allergy.

When a dog ingests too much Banamine, or experiences allergic reactions, it may vomit, have diarrhea, and show a lack of appetite and energy.

When Banamine is given in higher doses, there is a risk of the dog having kidney impairment or stomach ulceration. According to a study by Stegelmeier (1988), Banamine could cause gastric ulcerations when combined with endotoxin.

An experiment in 1999 was conducted among dogs that received Banamine at a dose of 2mg per body weight kilogram. The drug was administered through oral, subcutaneous, and intravenous means, and has resulted in an increase in plasma concentrations after treatment.

In addition, dogs suffered from anorexia, melena, fecal blood, aggressiveness, constipation, icterus, adipsia, colitis, abdominal pain, bleeding, weight loss, and skin reactions after receiving higher dosages of Banamine.

Cost of Banamine

A 100 ml bottle of Banamine costs $22.95, while a 250 ml bottle is priced at $45.95.

Interaction with Other Drugs

Banamine has contra-indications with certain drugs such as corticosteroids, aminoglycoside antibiotics, aspirin, warfarin, and heparin.

Ingredients in Banamine

Each ml of Banamine has 50mg of Flunixin, 2.5 mg Sodium formaldehyde sulfoxylate, 4.0mg diethanolamine, 0.1 mg edentate disodium, 5.0mg of phenol, 207.2 mg of propylene glycol, water, and hyrdrochloric acid.

Banamine Alternatives

Because of the toxicity present in Banamine, safer alternatives have been recommended. Fortunately, there is a “natural” Banamine that can relieve pain in dogs. A homeopathic formula can also relieve inflammation of muscles, joint pain, and even knee pain.

A better option is to use CBD oil for dogs with arthritis. Cannabidiol, a compound from hemp, has been found to be an effective remedy for people and animals with joint problems. But, unlike its cousin marijuana, CBD is free of THC, the compound that gives users a feeling of being high. This makes CBD safe for dogs.

CBD oil does not only reduce pain and swelling, but it also increases a dog’s appetite, reduces anxiety and instances of seizure, and staves off cancer risks.

CBD oil is also best taken by senior and disabled dogs to improve their mobility. Since dogs have their own endocannabinoid system (ECS), they easily and naturally respond to cannabinoids found in the hemp oil. CBD can be given topically, or as a supplement.

Other benefits of CBD oil as Banamine alternative are as follows:

It helps dogs manage their pain. Whether the pain developed because of an injury, surgical procedure, arthritis, or hip dysplasia, CBD can improve the dog’s threshold of pain while alleviating the pain it feels.

CBD oil also fights off inflammation in older and handicapped canines. When taken orally, CBD oil can effectively treat inflammation and bring the swollen part of the animal back to normal.

Evidence of toxicity among dogs has yet to be established, and the US Food and Drug Administration has not yet issued a dosage chart. However, a number of cases reported by pet owners have pointed to CBD oil as the better treatment method for dogs with muscle and joint problems.

If you are going to look for CBD oil for dogs, make sure the oil is indeed intended for dog use. There are CBD oil products in the market that serve specific uses (like as treatment for humans, for example).

The oil should have also been tested and passed quality standards. Organic and full spectrum CBD oil is also better than those combined with synthetic ingredients. Full spectrum CBD oil has the important ingredients and compounds present in the hemp plant. This means that a dog receiving CBD oil as treatment generally gets the wonderful medicinal benefits of the plant itself.

It will also help to investigate the CBD content in the product. Some products declare they have CBD, when in fact the CBD content is so small it does not help much in treating dogs.

Finally, look for CBD oil that supports animal welfare. This ensures that you are buying from companies that advocate the safety of dogs.

Conclusion

Dogs need not suffer pain and inflammation, or toxicity from NSAIDs.  The health and wellness sector highlights the use of natural and organic alternatives in treating medical conditions, and dogs are not exempted from these breakthroughs. Banamine may be effective, but it could also put your dog’s life in danger.

References

https://www.thepetplace.com/article/drug-library/flunixin-banamine-for-dogs-and-cats/

https://www.aavpt.org/

https://www.ncbi.nlm.nih.gov/m/pubmed/3042277/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241751/

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vetprofen for dogs side effects and alternatives

Vetprofen For Dogs Side Effects & Vetprofen Alternatives

Vetprofen is one of the popular remedies for dogs suffering from inflammation and pain caused by joint problems and osteoarthritis. It is known to give comfort to dogs, helping them become mobile and active after several days of treatment.

What Is Vetprofen for Dogs?

Vetprofen is a powerful pain treatment for dogs that undergo soft tissue or orthopedic surgery. Veterinarians typically administer this drug approximately 2 hours prior to the surgical procedure, and recommend that your dog is treated for a short period after going home.

It is also prescribed to relieve the discomfort that arthritis brings. The common form of this debilitating condition is osteoarthritis. It is caused by the “wear and tear” of the joint cartilages that results to your dog’s lameness or limping, decreased movement, stiffness of the joints, and reluctance to climb the stairs, run, stand, or jump.

It is available in tablet form, and given to dogs by mouth.

Dosage of Vetprofen

Before you decide if Vetprofen is good for your dog, consider the risks and benefits. It is necessary to follow the recommended dosage of the veterinarian to prevent adverse effects. He will recommend the right dosage for your dog, usually the lowest effective dose within the shortest duration.

The recommended dosage is 2 mg/pound (4.4 mg/kilogram) of body weight daily. There is an option is to divide the total daily dose by 1 mg/pound (2.2 mg/kilogram) two times a day. Caplets are scored and the dosage can be calculated in half-caplet increments. It can be taken with or without food.

This FDA-approved drug for dogs is available in 25, 75, and 100 milligrams. Caplets are in a 240-count bottle, while the flavored tablets are in a 180-count bottle.

  • For 5-10 and 11-15-pound dogs, the 25 mg variant is recommended. It allows 12.5 mg (1/2 caplet) dosage and 25 mg (1 caplet) dosage.
  • For 16-20 and 31-40 pound dogs, 75 mg is recommended. It provides 37.5 mg (1/2 caplet) and 75 mg (1 caplet) dosage.
  • For 21-30, 41-60, 61-90, and 90-120-pound dogs, use 100 mg. It lets you give a 50 mg (1/2 caplet), 100 mg (1 caplet), 150 mg (1 ½ caplets), or 200 mg (2 caplets) dosage.

In case your dog accidentally ingests more than the recommended dosage, contact the veterinarian right away to address the issue, and prevent potential harm.

Side Effects of Vetprofen

Like other NSAID (non-steroidal anti-inflammatory drugs), Vetprofen can bring potential adverse effects to your pet dog. As the pet parent, you need to get information regarding the clinical signs linked with drug intolerance. Be aware also that some serious side effects occur with or without warning and may even result in death.

Here are some of the side effects:

  • Decreased appetite
  • Diarrhea
  • Vomiting
  • Increased water consumption
  • Increased urination
  • Dark or tarry stools
  • Pale gums/yellowing of the gums or whites of the eyes due to jaundice
  • Skin changes like redness or scabs
  • Excessive scratching
  • Lethargy
  • Incoordination or difficulty of movement
  • Behavioral changes that include aggression
  • Seizure

As soon as you observe any of these symptoms, discontinue administering the drug, and promptly call your dog’s veterinarian for proper treatment. It is also important to take your dog to the clinic for a periodic follow up during the drug administration to ensure optimum care, and avoid potential adverse effects.

With veterinary care, withdrawal of the drug, and immediate recognition of the symptoms, your dog can avoid more serious side effects.

The Cost of Vetprofen

It is considered an economical drug for pain management. The price varies, depending on the distributor, pharmacy, or store. However, the 25 mg caplet usually costs around $0.37, the 75 mg is $0.44/caplet, and the 100 mg is $0.55/caplet.

  • The 60-count of 25 mg caplet is around $22- $25 and the 240-count is $90 -$95.
  • The 60-count of 75 mg caplet costs around $26-$28 and 240-count is $106- $110.
  • The 60-count of 100 mg caplet costs approximately $33-$35, while the 240-count is $134-$137.

Interaction with Other Drugs

It is important to tell the vet if your dog had previous experience of an allergic reaction, digestive upset, or bleeding ulcer to other NSAIDs. To prevent more serious effects, tell him if the dog has a kidney or liver disease, of if it is pregnant, nursing, or taking medicines that may cause counter-reaction.

Discuss the medicines that you intend to give to your dog while administering Vetprofen, especially the ones that you can buy without a prescription.

It is unwise to give Vetprofen with other types of NSAIDs like aspirin, etodolac, and deracoxib, among others) or with steroids like the cortisone, triamcinolone, prednisone, and dexamethasone.

Ingredients in Vetprofen

Vetprofen belongs to the propionic acid class of non-steroidal anti-inflammatory drugs (NSAID), along with ibuprofen, ketoprofen, and naproxen. Its most active ingredient is Carprofen, the nonproprietary term for 6-chloro-a-methyl-9H-carbazole-2-acetic acid or substituted Carbazole.

Carprofen effectively blocks the production of prostaglandins, the chemical substance of the body that triggers inflammation. Due to its potent components, the Federal Law restricts any use of this drug without the prescription of licensed veterinarians.

Vetprofen Alternative Pain Medications

Aside from the Vetprofen, other NSAIDs for dogs are Novox or Rimadyl, Deramaxx, Previcox, and Metacam.

The other popular drugs for canine osteoarthritis include:

  • Galliprant is a piprant antagonist medicine that inhibits the stimulation of prostaglandins.
  • Adequan is an injectable joint protectant that soothes and lubricates joints, relieves pain, lessens joint damage, and stimulates repair of cartilage.
  • Corticosteroids like prednisone, dexamethasone, and methylprednisolone are helpful.
  • Painkillers like Gabapentin and Tramadol are also good.

Gabapentin helps to treat pain caused by damaged nerves. It usually makes dogs sleepy during the first few days, but eventually goes away.

Tramadol (Ultram) is a synthetic opioid that acts as norepinephrine reuptake inhibitor and serotonin. It works like other mild opioid drugs and usually administered to aging dogs.

  • Supplements like Chondroitin and Glucosamine help the cartilage to self-repair and make the swelling go away.
  • Medical Marijuana & Other Cannabis Products with cannabinoids (CBD) offer therapeutic properties.
  • CBD Oil is an excellent alternative that provides safe and effective relief for dogs with arthritis, and other health issues like stress, anxiety, nausea, seizures, gastrointestinal conditions, back pain, and other symptoms of cancer.

With proper dosage, the oil has no life-threatening side effects. Look for organic CBD oil to ensure that it does not contain solvents, fungicides, or pesticides.

References:

https://www.medi-vet.com/Vetprofen-carprofen-Caplets-25mg-p/16508.htm

https://www.myhappypets.com/general-health/product/vetprofen

https://www.heartlandvetsupply.com/p-2842-vetprofen-caplets.aspx

https://entirelypetspharmacy.com/vetprofen-100-mg-per-caplet.html

https://www.drugs.com/pro/vetprofen.html

https://www.whole-dog-journal.com/health/prescription-drugs-for-dogs-arthritis-pain/

https://pets.webmd.com/dogs/guide/dog-pain-medications#1

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previcox for dogs side effects and alternatives

Previcox for Dogs Side Effects & Previcox Alternatives

Side Effects of Previcox for Dogs & Alternatives 

Even when your dog is well-taken care of, pain and illness will still be inevitable. Every now and then, you’ll need to take your dog to the vet for a check-up or a fix-up. And these visits to the vet will become more frequent as your dog grows older and starts to experience age-related conditions.

The most common conditions that dogs suffer from when they age are joint problems. Sadly, when these problems occur, they become part of a dog’s everyday life, which they don’t like—because it’s painful.

Joint problems are commonly managed by giving dogs prescribed painkillers along with supplements. NSAIDs (non-steroidal anti-inflammatory drugs) are the usual painkillers that vets prescribe for joint pain. And one of the most popular NSAIDs for dogs is Previcox, which is the focus of this subject.

What Is Previcox?

Previcox (firocoxib) is an NSAID that’s commonly prescribed for dogs with degenerative joint diseases (DJD) such as osteoarthritis. Like most NSAIDs, it works by blocking the chemical messengers responsible for inflammatory responses that cause pain and swelling in the affected joints.

What Is the Dosage for Previcox?

The dosage for Previcox and the frequency of intake depend on the dog’s mass or weight. For each pound of mass, the recommended amount is 2.27 mg per day.

Previcox is dispensed in two forms: 57 mg and 227 mg chewable tablets.

  • The 57 mg tablet is prescribed for dogs weighing 12.5 pounds and above (but below 36 pounds).
  • The 227 mg tablet is prescribed for larger dogs weighing 36 pounds and above (up to 240 pounds).

The tablet may be given whole or broken into half, depending on the dog’s weight range and the prescribed frequency of intake. Previcox is usually taken only once a day.

What Are the Side Effects of Previcox?

Previcox can provide several beneficial effects on your dog, including:

  • It relieves or lessens joint pain.
  • It lessens swelling around the joints.
  • It helps increase the ability to move around more easily.
  • It helps improve mood due to the reduction of pain.

But like any other drug, Previcox can cause some unwanted effects along with its benefits. While on Previcox, the dog may experience any of the following side effects:

  • Diarrhea
  • Upset stomach
  • Changes in appetite
  • Nausea and vomiting
  • Flatulence or gassiness
  • Mild skin irritations

It’s also important to note that some dogs may develop allergic reactions to Previcox. The symptoms of an allergic reaction may include the following:

  • Swelling of the tongue or lips
  • Swelling of the mucous linings of the throat that may cause breathing difficulties
  • Hives or rashes
  • Itchiness

Other adverse reactions that you should watch out for are:

  • Jaundice (yellowing of the skin and mucous linings of the mouth and eyes)
  • Abdominal pain
  • Bloody or tarry stool
  • Bloody vomit
  • Unexplained bruises or bleeding
  • Sudden loss of appetite
  • Sudden weight gain

If you notice your dog develop any allergic or adverse reaction, you should stop giving Previcox and consult with the vet immediately.

How Much Is Previcox?

Previcox 57 mg and 227 mg can be bought in packs of 10 or 60. They’re widely available in pet pharmacies and some pet stores. The price per bottle may vary, depending on the pharmacy or store, and your location.

  • The cost of a 10-pack Previcox 57 mg is $16 to $24. The 60-pack can cost between $90.00 and $133.00.
  • The cost of a 10-pack Previcox 227 mg is $35 to $51, while the 60-pack can cost around $200 to $286.

Both 57 mg and 227 mg tablets are also available online. Just remember that a prescription is needed to dispense Previcox.

Main Ingredient of Previcox

The main active ingredient used in Previcox is Firocoxib.

Firocoxib is a COX-2 selective NSAID. It is clinically developed to provide pain relief by blocking only certain COX-2 enzymes to reduce prostaglandin production.

Prostaglandins are responsible for activating inflammatory responses in the body. They can be produced through a conversion process involving some enzymes. These enzymes are either COX-1 or COX-2 enzymes.

Interaction with Other Drugs

NSAIDs like Previcox can interact with other drugs in a negative way. If your dog is taking other medications or supplements that your vet doesn’t know about, you should disclose the information.

Some of the drugs that Previcox may interact (or counteract) with include:

  • Phenobarbitals
  • Benzodiazepines
  • Aminoglycosides
  • Furosemide
  • Spironolactone
  • Gingko
  • Ginger
  • Ginseng
  • Garlic
  • Meadowsweet Willow

Alternatives to Previcox

Previcox may or may not produce any side effect in your dog while taking the medication. However, Previcox is a synthetic drug that may gradually take a toll on your dog’s health over time.

When Previcox (or any NSAID) is taken long-term, your dog may gradually develop some irreversible health problems. These problems may arise from organ damage due to frequent and prolonged use of Previcox and/or other NSAIDs.

Over time, your dog might develop any of the following problems:

  • Liver failure
  • Kidney failure
  • Gastrointestinal ulcers
  • Bleeding problems

Other than these problems, your dog may also develop increased tolerance or resistance to the drug’s effects. This means that the drug may no longer provide the same level of pain relief. The dog’s body would become so used to the drug that higher doses will be needed to achieve the desired outcome.

Because of these undesirable effects, many vets and pet care experts now recommend safer and more natural alternatives to Previcox (and other NSAIDs). And one of the most recommended alternatives is the use of CBD oil for dogs.

CBD oil has been found effective in managing pain and swelling in dogs with DJD. It is a natural anti-inflammatory derived from the cannabis hemp plant and specially formulated to work within the dog’s “endocannabinoid” system (ECS).

 

ECS helps regulate the body’s inflammatory responses without artificially inhibiting other bodily processes. Instead of “inhibiting” something, ECS works out to “balance” the processes so that no process would overturn another process and cause reactions (such as inflammatory responses) from the imbalance.

When used in pain management, CBD oil reinforces the ECS and supports its functions to fight off imbalances that stimulate inflammatory responses.

Aside from CBD oil, other safer alternatives to Previcox include:

  • Herbal treatment (Yucca, Turmeric, Feverfew and Cayenne)
  • Essential oils (Ginger, Peppermint and Lavender)
  • Supplements (Glucosamine and Chondroitin Sulfate, Krill oil, and MSM)
  • Non-invasive or minimally invasive methods (acupuncture, laser therapy, and pulsed electromagnetic therapy)

When your dog is in pain because of DJD, you might agree to just about anything that’ll help lessen the pain. If the vet prescribes Previcox, it’s okay to follow the prescription. However, you should also consider the long-term effects on your dog.

 

When prescribed with Previcox, you must also ask your vet about alternative treatments that your dog may also benefit from. Expressing your concern and intention to try other options is the first step to avoiding any drug’s unwanted effects.

References:

https://www.honestpaws.com/blogs/medication/previcox
https://www.certapet.com/previcox/

The Problem With NSAIDs For Dogs


http://dogkinetics.com/300/dog-health/alternatives-to-nsaids-rimadyl-previcox-metacam-deramaxx-etc

Anti-Inflammatory For Dogs: Why CBD Might Be The Safest Natural Option For Your Dog


https://www.vin.com/apputil/content/defaultadv1.aspx?id=5709854&pid=11372&print=1

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