24 November, 2020

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Previcox for Dogs Side Effects & Previcox Alternatives

Side Effects of Previcox for Dogs & Alternatives 

Even when your dog is well-taken care of, pain and illness will still be inevitable. Every now and then, you’ll need to take your dog to the vet for a check-up or a fix-up. And these visits to the vet will become more frequent as your dog grows older and starts to experience age-related conditions.

The most common conditions that dogs suffer from when they age are joint problems. Sadly, when these problems occur, they become part of a dog’s everyday life, which they don’t like—because it’s painful.

Joint problems are commonly managed by giving dogs prescribed painkillers along with supplements. NSAIDs (non-steroidal anti-inflammatory drugs) are the usual painkillers that vets prescribe for joint pain. And one of the most popular NSAIDs for dogs is Previcox, which is the focus of this subject.

What Is Previcox?

Previcox (firocoxib) is an NSAID that’s commonly prescribed for dogs with degenerative joint diseases (DJD) such as osteoarthritis. Like most NSAIDs, it works by blocking the chemical messengers responsible for inflammatory responses that cause pain and swelling in the affected joints.

What Is the Dosage for Previcox?

The dosage for Previcox and the frequency of intake depend on the dog’s mass or weight. For each pound of mass, the recommended amount is 2.27 mg per day.

Previcox is dispensed in two forms: 57 mg and 227 mg chewable tablets.

  • The 57 mg tablet is prescribed for dogs weighing 12.5 pounds and above (but below 36 pounds).
  • The 227 mg tablet is prescribed for larger dogs weighing 36 pounds and above (up to 240 pounds).

The tablet may be given whole or broken into half, depending on the dog’s weight range and the prescribed frequency of intake. Previcox is usually taken only once a day.

What Are the Side Effects of Previcox?

Previcox can provide several beneficial effects on your dog, including:

  • It relieves or lessens joint pain.
  • It lessens swelling around the joints.
  • It helps increase the ability to move around more easily.
  • It helps improve mood due to the reduction of pain.

But like any other drug, Previcox can cause some unwanted effects along with its benefits. While on Previcox, the dog may experience any of the following side effects:

  • Diarrhea
  • Upset stomach
  • Changes in appetite
  • Nausea and vomiting
  • Flatulence or gassiness
  • Mild skin irritations

It’s also important to note that some dogs may develop allergic reactions to Previcox. The symptoms of an allergic reaction may include the following:

  • Swelling of the tongue or lips
  • Swelling of the mucous linings of the throat that may cause breathing difficulties
  • Hives or rashes
  • Itchiness

Other adverse reactions that you should watch out for are:

  • Jaundice (yellowing of the skin and mucous linings of the mouth and eyes)
  • Abdominal pain
  • Bloody or tarry stool
  • Bloody vomit
  • Unexplained bruises or bleeding
  • Sudden loss of appetite
  • Sudden weight gain

If you notice your dog develop any allergic or adverse reaction, you should stop giving Previcox and consult with the vet immediately.

How Much Is Previcox?

Previcox 57 mg and 227 mg can be bought in packs of 10 or 60. They’re widely available in pet pharmacies and some pet stores. The price per bottle may vary, depending on the pharmacy or store, and your location.

  • The cost of a 10-pack Previcox 57 mg is $16 to $24. The 60-pack can cost between $90.00 and $133.00.
  • The cost of a 10-pack Previcox 227 mg is $35 to $51, while the 60-pack can cost around $200 to $286.

Both 57 mg and 227 mg tablets are also available online. Just remember that a prescription is needed to dispense Previcox.

Main Ingredient of Previcox

The main active ingredient used in Previcox is Firocoxib.

Firocoxib is a COX-2 selective NSAID. It is clinically developed to provide pain relief by blocking only certain COX-2 enzymes to reduce prostaglandin production.

Prostaglandins are responsible for activating inflammatory responses in the body. They can be produced through a conversion process involving some enzymes. These enzymes are either COX-1 or COX-2 enzymes.

Interaction with Other Drugs

NSAIDs like Previcox can interact with other drugs in a negative way. If your dog is taking other medications or supplements that your vet doesn’t know about, you should disclose the information.

Some of the drugs that Previcox may interact (or counteract) with include:

  • Phenobarbitals
  • Benzodiazepines
  • Aminoglycosides
  • Furosemide
  • Spironolactone
  • Gingko
  • Ginger
  • Ginseng
  • Garlic
  • Meadowsweet Willow

Alternatives to Previcox

Previcox may or may not produce any side effect in your dog while taking the medication. However, Previcox is a synthetic drug that may gradually take a toll on your dog’s health over time.

When Previcox (or any NSAID) is taken long-term, your dog may gradually develop some irreversible health problems. These problems may arise from organ damage due to frequent and prolonged use of Previcox and/or other NSAIDs.

Over time, your dog might develop any of the following problems:

  • Liver failure
  • Kidney failure
  • Gastrointestinal ulcers
  • Bleeding problems

Other than these problems, your dog may also develop increased tolerance or resistance to the drug’s effects. This means that the drug may no longer provide the same level of pain relief. The dog’s body would become so used to the drug that higher doses will be needed to achieve the desired outcome.

Because of these undesirable effects, many vets and pet care experts now recommend safer and more natural alternatives to Previcox (and other NSAIDs). And one of the most recommended alternatives is the use of CBD oil for dogs.

CBD oil has been found effective in managing pain and swelling in dogs with DJD. It is a natural anti-inflammatory derived from the cannabis hemp plant and specially formulated to work within the dog’s “endocannabinoid” system (ECS).


ECS helps regulate the body’s inflammatory responses without artificially inhibiting other bodily processes. Instead of “inhibiting” something, ECS works out to “balance” the processes so that no process would overturn another process and cause reactions (such as inflammatory responses) from the imbalance.

When used in pain management, CBD oil reinforces the ECS and supports its functions to fight off imbalances that stimulate inflammatory responses.

Aside from CBD oil, other safer alternatives to Previcox include:

  • Herbal treatment (Yucca, Turmeric, Feverfew and Cayenne)
  • Essential oils (Ginger, Peppermint and Lavender)
  • Supplements (Glucosamine and Chondroitin Sulfate, Krill oil, and MSM)
  • Non-invasive or minimally invasive methods (acupuncture, laser therapy, and pulsed electromagnetic therapy)

When your dog is in pain because of DJD, you might agree to just about anything that’ll help lessen the pain. If the vet prescribes Previcox, it’s okay to follow the prescription. However, you should also consider the long-term effects on your dog.


When prescribed with Previcox, you must also ask your vet about alternative treatments that your dog may also benefit from. Expressing your concern and intention to try other options is the first step to avoiding any drug’s unwanted effects.


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