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side effects of meloxicam for dogs and alternatives

Meloxicam For Dogs Side Effects & Meloxicam Alternatives

Side Effects Of Meloxicam For Dogs & Alternatives

If you have a pet dog, then you may have already seen the drug Meloxicam in stores. It’s typically sold by its brand name Metacam and is often bought by dog owners who want their pets to get better from certain illnesses and disorders. Keep in mind that the brand Mobic, which is also a Meloxicam medication, is only for humans. Hence, you should never give it to your pet.

What Is Meloxicam for Dogs?

Meloxicam is a medication that is used to reduce inflammation, stiffness, and pain in dogs that have osteoarthritis and similar conditions. It’s also used to treat the symptoms of bone or muscle disorders. It reduces the hormones that cause inflammation and pain.

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID). It has been approved by the Food and Drug Administration (FDA) and can be obtained with a prescription from a veterinarian.

Aside from treating various conditions, it can also be used to alleviate the pain caused by a surgical procedure. So, if your dog needs to undergo a surgery, the veterinarian may recommend and prescribe the drug. Likewise, it may be used to alleviate the pain caused by an injury.

When this happens, see to it that you abide by the guidelines for dosages and proper storage for the drug. You should also know about the possible side effects of meloxicam in dogs. This way, you can be prepared when it comes to dealing with any signs and symptoms.

Dosage of Meloxicam

Usually, the initial dosage given to dogs ranges from 0.09 to 0.1 milligram per pound. Then, this dosage increases to 0.045 to 0.05 milligram per pound. Meloxicam has to be given to the dog orally once per day.

The veterinarian of your dog would give you guidelines and instructions with regard to the proper measurement of its medication. You can give your dog tablets with or without food. However, you need to make sure that he drinks sufficient amounts of water every day.

Aside from tablets, you can also purchase Metacam in liquid form. You can add this liquid medication to the food of your dog if he is not inclined to taking tablets. Consult your veterinarian regarding the most ideal form of Meloxicam.

The veterinarian may also adjust the dosage of your dog based on his response to the medication. Ideally, you should give your pet the lowest possible dosage and still be able to relieve its unpleasant symptoms.

In addition, you can find Meloxicam in injectable solutions. Your dog’s veterinarian would give you guidelines and instructions on how to properly and safely administer this solution.

See to it that you always follow the prescribed dosage of your dog’s veterinarian. Otherwise, you can risk overdosing your pet. This can have unpleasant results, such as dizziness, vomiting, headache, fainting, seizures, slowed breathing, and cardiac arrest among others.


Side Effects of Meloxicam in Dogs

Your dog can experience negative side effects if it takes too much Meloxicam or its body does not properly adapt to the drug. Gastrointestinal upset is the most common side effect of Meloxicam.

If you notice the symptoms getting worse, you have to contact the veterinarian right away. Your dog may either be given an adjusted dosage or an alternative treatment method.

Aside from gastrointestinal upset, your dog may also experience the following side effects after taking Meloxicam: bloody vomit, bloody or black stool, weight gain or swelling due to fluid retention, fatigue, increased urination, increased thirst, yellowing of eyes, skin, and gums, itchiness, weight loss, abdominal pain, stomach ulcers, and changes in behavior.

Furthermore, your dog may have a risk of allergic reaction, which can result in anaphylaxis. So, if you notice any signs of allergic reaction, such as hives, swelling, and difficulty breathing, you must contact the veterinarian right away.

Pregnant dogs as well as puppies should not be allowed to take this drug. Do not forget to tell your dog’s veterinarian about any existing medical condition, especially if it is cardiovascular or renal.

The veterinarian must also be aware of any other medications that you give your dog. Take note that any drug, including over-the-counter ones, may have a negative reaction towards Meloxicam.

Cost of Meloxicam

Meloxicam is actually one of the most affordable medications for alleviating pain and inflammation. Nonetheless, its price may vary depending on where you bought it. You can buy Metacam online and in local stores. It’s generally sold per tablet at $0.51 to $0.73. Each tablet is typically 7.5mg.

For instance, you can check out Heartland Vet Supply as well as KVSupply for stocks and prices.


Interaction with Other Drugs

When you give Meloxicam to your dog, you have to refrain from giving it other types of medication, including prednisone, tramcinolone, dexamethasone, and cortisone among other corticosteroids and NSAID’s.

Make sure that you inform the veterinarian if you have given your dog etodolac, piroxicam, carprofen, furosemide, warfarin, or any over-the-counter drug for cough, pain, cold, or allergy.

Ingredients In Meloxicam

Every milliliter of Metacam (Meloxicam) tablet contains 0.5 to 1.5 milligrams of meloxicam and 1.5 milligrams of sodium benzoate. Its suspension formulation smells like honey and is yellowish in color. Non active ingredients may include silicon dioxide, sodium benzoate, sorbitol, glycerin, saccharin sodium, xylitol, and citric acid monohydrate.

Meloxicam Alternatives

As you know, Meloxicam can have unpleasant side effects. Hence, you should consider alternative treatment methods that have natural healing properties.

Acupuncture – It is not only good for humans, but it is ideal for dogs as well. This Chinese treatment method can help relieve chronic pain and acute pain that is associated with degenerative joint and bone conditions as well as osteoarthritis.

Turmeric – It has natural antioxidant and anti-inflammatory properties that makes it effective in relieving pain. It is also ideal for treating joint conditions such as arthritis.

Yuca – According to holistic veterinarians, this root has a fifty to eighty percent success rate in treating rheumatoid arthritis and osteoarthritis in dogs. It can provide relief for joint inflammation and pain.

CBD Oil – For years, dog owners have turned to CBD oil for relieving various ailments in their pets. CBD oil is actually effective in relieving arthritis and joint pain, relieving anxiety, and reducing inflammation. It is also effective in reducing vomiting and nausea, suppressing muscle spasms, reducing seizures, and improving sleep.

Moreover, it is effective in improving appetite as well as improving nervous system and digestive health. With this being said, you can conclude that CBD oil is a much better alternative to prescription drugs, such as Metoxicam, in many ways.

Due to its natural healing properties, your pet can avoid experiencing unpleasant side effects and adverse reactions to unnatural ingredients. Holistic alternatives can be just as good as prescription medication, but without the harsh side effects.


Side effects of metacam for dogs

Metacam For Dogs Side Effects & Metacam Alternatives

Side Effects of Metacam For Dogs & Alternatives

What is Metacam for Dogs?

Metacam or Meloxicam is a non-steroidal anti-inflammatory drug (NSAID). This is used to treat stiffness, inflammation, and pain in dogs. Metacam is also used to reduce fever.

Metacam’s effect is seen 8 hours after administration. If giving the dog Metacam for the first time, it may take 3-4 days to take effect. Stop giving the drug if after 10 days there is still no improvement on the dog’s condition.

Dosage of Metacam

Oral suspension Metacam is given 0.2 mg Metacam per kilogram of body weight on the first dose. The following doses or maintenance dose is 0.1 mg per kilogram of body weight.

The oral suspension Metacam should be given with food. This oral suspension type come in 10, 32, 100 or 180 mL bottles.

Metacam tablet form is in 7.5 mg dosage and can be given with or without food. The initial dose is 0.1 mg per pound of body weight. After that, the dose will be 0.05 mg per pound of body weight.

Metacam is given to the dog once a day.

For dogs that are less than 10 pounds, Metacam should be given with food. Never administer the drug directly into the dog’s mouth. The dose is two drops per pound of body weight. This is for the 0.5 mg per mL concentration.

For dogs over 10 pounds (4.5 kilograms) use the measuring syringe provided. This is designed to administer the daily maintenance dose which is 0.05 mg/lb.

To get the accurate dosage per the dog’s body weight, round off the dog’s weight to the nearest 1 pound increment.


Metacam should not be given to dogs aged 6 weeks and below. Lactating, breeding and pregnant dogs should not be given Metacam.

Dogs with existing cardiovascular diseases and renal conditions should not be given Metacam. This can cause further complications on the dog.

It is important to tell your veterinarian about the medications the dog is taking in. This is to prevent harmful drug interactions from happening.

Side effects Metacam for dogs

NSAIDs such as Metacam can affect the kidney and liver of the dog in long term use.

Other side effects of Metacam are:

  • Blood in vomit
  • Weight loss
  • Itchiness
  • Behavioral changes
  • Stomach ulcers
  • Black or bloody stool
  • Fatigue or weakness
  • Swelling or weight gain- this is due to fluid retention
  • Abdominal pain or tenderness
  • Increased thirst
  • Increased urination
  • Jaundice- yellowing of the eye, skin, and gums

There are reported cases of allergic reactions as well. In a worst case scenario these allergic reactions can lead to anaphylaxis. Anaphylaxis happens when the airway constricts preventing oxygen to be distributed to the lungs.

Metacam storage

Metacam should be stored at a controlled room temperature. The temperature should be between 59 degrees and 86 degrees Fahrenheit.

Metacam Cost

  • A bottle of Metacam that is 1.5 mL/32 mL cost around 57 dollars. A 100 mL bottle cost around 120 dollars.
  • A bottle of 180 mL Metacam is around 136 to 175.69 dollars.
  • A bottle of 1.5 mL/10 mL Metacam cost around 15 dollars.


Interaction of Metacam to other drugs

Metacam should not be given with other NSAIDs. These include Firocoxib, Aspirin and Carprofen. This can inhibit the function of and normal response of the medication to the dog’s body.

Corticosteroids such as prednisone and cortisone should be avoided when the dog is taking in Metacam. Corticosteroids can make the side effects of Metacam worst.

Active Ingredients of Metacam

The active ingredient of Metacam is meloxicam. A bottle of Metacam has 1.5 mg of meloxicam. It also contains 1.5 mg of sodium benzoate. This is equivalent to 0.05 milligrams per drop.

Other ingredients include sodium citrate dihydrate colloidal silicon dioxide, povidone, microcrystalline cellulose and magnesium stearate.

Oral suspension Metacam substances are suspended in a yellowish solution with an odor of honey.

Metacam alternatives

Metacam is an effective drug for dog pain. There are also other natural remedies for dog pain and stiffness.

Keeping the dog in a healthy lifestyle is one that helps. This includes proper diet and regular exercise.

The following are some anti-inflammatory and pain remedies:

Fish oil – Fish oil helps with pain and inflammation. Fish oil has omega 3 that reduces inflammatory substances in the dog’s body.

Arnica – Arnica is a plant that is mostly grown in Europe and North America. Arnica is extracted from the flowers.  The compounds inside the plant help treat inflammation.

There are different forms of arnica. It can be in oil, gel, or capsule variants.

Hydrotherapy- This therapy involves the dog swimming in a purpose-built pool. This helps ease pain for dogs with stiff joints. Hydrotherapy also helps build muscle mass to support the joints.

Glucosamine – This is a popular anti-inflammatory remedy. Glucosamine is mainly used for joint problems. This includes joint inflammation/ pain, arthritis and dysplasia.

Glucosamine helps ease issues in the digestive system.  Glucosamine treats joint inflammation by producing more synovial fluid and cartilage.

Yucca – Yucca is an anti-inflammatory plant grows in Central and South America. Yucca contains saponins found in the roots of the plant. Saponin substances are as effective as some steroid medications. This compound is the one that reduces inflammation.

Yucca is an effective remedy but it can irritate the stomach. Yucca is not for long-term use. It works best with minor conditions.

Acupuncture – Acupuncture is a traditional Chinese medical practice. This involves inserting small hair-like needles into the skin.The needles are inserted in the part to be treated. This are called acupuncture points.  This helps reduce inflammation, ease pain and improve overall health of the dog.

CBD oil – CBD stands for Cannabidiol. This is also known as hemp oil.  CBD oil is one of the known and effective alternatives for Metacam.

It is considered safe because it is derived from the hemp plant. This oil extract helps solve inflammation issues by activating the endocannabinoid system of the dog.

CBD is also used to treat colitis, gastritis, dysplasia’s, inflammatory bowel disease (IBD), and arthritis.

CBD oil also provides protection against diabetes and tumor growth.



side effects of ibuprofen for dogs and alternatives

Ibuprofen For Dogs Side Effects & Ibuprofen Alternatives

Side Effects Of Ibuprofen For Dogs & Alternatives

Seeing your dog in pain is upsetting. Your primary concern is to find an immediate solution to alleviate the pain. Sometimes, you tend to use over-the-counter (OTC) pain medications that only work on humans. This can put your pet in so much danger. It can lead to more serious complications and death.

To prevent this, always consult your vet about the right medications to use. Do not use OTC pain meds specifically for human consumption.

What is Ibuprofen for Dogs

Ibuprofen is a Nonsteroidal Anti-inflammatory Drug (NSAID) that is mainly used to treat pain and inflammation in humans. It can also be used to treat headache, fever, and arthritis. In humans, Ibuprofen works by inhibiting cyclooxygenase, an enzyme that produces prostaglandins. These enzymes bring fever-like symptoms like pain and inflammation. Prostaglandin-inhibiting drugs like Ibuprofen help relieve these symptoms.

Veterinarians do not recommend the use Ibuprofen in dogs since it can cause adverse reactions to canines. Dogs can also get easily overdosed by Ibuprofen. Prostaglandins play important roles in a canine’s body such as normal blood clotting and good blood flow to the kidneys. These enzymes also help protect the gastrointestinal tract (GI) of a dog. When dogs ingest Ibuprofen, the drug will destroy the prostaglandin enzymes that are beneficial to dogs.

Dosage of Ibuprofen

Normally, the vet does not prescribe and administer Ibuprofen medication to dogs. But in some special cases like eye inflammation, the pain brought by cancer, and arthritis, they give a really small dose of Ibuprofen. The usual drug dosage is 2.5 mg – 4 mg per 5-8 kg twice a day or every 12 hours. It should strictly given by the doctor, do not attempt to do it yourself

Side Effects of Ibuprofen

Ibuprofen, when ingested by dogs, spreads rapidly in the bloodstream. The components of this drug are easily absorbed in their stomach and intestines. Within a short period, your dog may experience allergic reactions and other symptoms.

The following are the side effects of Ibuprofen in dogs:

  • Gastrointestinal bleeding
  • Vomiting
  • Loss of appetite
  • Abdominal pain
  • Irregular bleeding
  • Pale gums
  • Liver and kidney failure (extreme cases)

When the owners accidentally give higher doses of Ibuprofen to their canine, this can lead to:

  • Change in behavior
  • Altered mental status
  • Episodes of seizure attacks
  • Coma
  • Death

Cost of Ibuprofen

A single 200-mg Ibuprofen oral capsule costs $1 – $2.13. A single 100-mg oral tablet costs $1.15 while a 200-mg oral tablet costs $1.35. One bottle of Ibuprofen oral drops (40mg/ml) costs $6.50-$8.30 while oral suspension (50mg/1.25ml) costs $11.50 – $12.

Interaction with Other Drugs

If your vet prescribed Ibuprofen to your canine, listen attentively to his instructions. Take note of the following:

  • Administering Ibuprofen with anticoagulants can be dangerous. Doing so will prolong the prothrombin time that can lead to bleeding.
  • Taking this drug with Cholestyramine may decrease its effect.
  • When used with Cyclosporine, this can damage the kidneys.
  • When Ibuprofen is mixed with diuretics, the diuretic med could be rendered ineffective.
  • Ibuprofen and Phenobarbital combination can reduce Ibuprofen’s effect.
  • Probenecid can increase the plasma concentration of Ibuprofen.

Ingredients in Ibuprofen

Ibuprofen contains the active ingredient Ibuprofen, a water-soluble substance. This NSAID is readily soluble in organic solvents like acetone and ethanol. Other inactive ingredients include hypromellose, colloidal silicon dioxide, magnesium stearate, and lactose monohydrate. As stated above, Ibuprofen is a prostaglandin-inhibiting drug. It also possesses antipyretic (anti-fever) and analgesic properties. Most components of Ibuprofen drug are dangerous to dogs and cats.

Ibuprofen Alternatives

As a dog owner, it is best to find the best alternative solution to help relieve your pup’s pain. Eliminating Ibuprofen as an alternative is one of the best solutions to do this. You can use the following Ibuprofen alternatives:

  1. NSAIDs for Dogs
  • Your vet will only use Ibuprofen to treat your dog’s pain if badly needed. Otherwise, he will prescribe the following NSAIDs that are specifically made for dogs:
  • Deramaxx
  • Rimadyl’
  • Previcox
  • Metacam
  • Tramadol
  • Amantadine
  • Gabapentin

If the pain seem tolerable, you can use more natural ways such as gentle massage and other therapies.

  1. Omega-3 fatty acids – Omega-3 are healthy fats that come from these fish sources – salmon, tuna, mackerel, herring, etc. These unique fatty acids act directly in different human and animal cells to relieve inflammation. Less inflammation can lead to decreased swelling, redness, and pain. Since most dogs love to eat fish meat, it can be a good alternative pain management solution for your canine.
  2. Joint Supplements – Joint supplements are one of the most effective chronic pain management for joint ailments such as arthritis in dogs. The most common joint supplement is glucosamine. This is a chondroprotective medication that cushions the cartilage while the body is trying to repair cartilage loss. Protecting cartilage means decreasing the pain and inflammation. Joint supplements like glucosamine, are administered orally.
  3. Acupuncture – This traditional Chinese medicine can help relieve muscle and joint pain, inflammation, and trauma. This can provide temporary or permanent pain solution to your canine. When thin needles are inserted to your pet’s body, it stimulates the nervous system and improves its blood circulation. Then, it releases good hormones that help soothe the pain and discomfort. Consult a licensed animal acupuncturist to do this.
  4. CBD Oil for Dogs – Cannabidiol (CBD) oil is a hemp plant extract that is becoming popular nowadays. The good thing about CBD oil is it is not psychoactive and is safe to your dogs. It only contains 0.3% of Tetrahydrocannabinol (THC) that brings psychological effects. This does not make your dogs “high”; instead, this can make them feel more relaxed and pain-free.
  • CBD oil contains a good amount of anti-inflammatory compound that helps stop inflammation or swelling. The presence of inflammation indicates pain.

Dog illnesses such as chronic cancer, arthritis, and severe joint injury can be extremely painful for your best buds. CBD oil acts directly to the affected site and provides immediate relief. This hemp extract can also help stabilize the mood of your canine and make him feel more relaxed. When your dog feels good, the pain can be eliminated quickly. Your best friend can now go back to his daily routines and be alive again.

  • To administer CBD oil to your dogs, use the following techniques:
  • Applying directly to your dog’s mouth
  • Incorporating to a treat
  • Mixing with foods and drinks

Your canine’s health is always a priority. Regularly check your pet for any pain and discomfort. Pain can be irritating to dogs. This too can change his behaviors and interactions with humans. When giving pain medications, try to avoid NSAIDs that can put your pup in danger. You should not administer Ibuprofen to your dog in any means. Your vet will decide whether to give this drug or not to your canine.

Using CBD oil is one of the best alternative pain treatments for your dogs. This hemp extract contains natural anti-inflammatory and analgesic properties. This also helps your canine feel more relaxed and stress-free. Cannabidiol is safe to use and effective if taken in the right dosage. For best results, consult your vet.


carprofen for dogs side effects alternatives

Carprofen For Dogs Side Effects & Carprofen Alternatives

Side Effects Of Carprofen For Dogs & Alternatives: What is Carprofen for Dogs?

Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic properties. It is used solely in veterinary medicine for treating dogs with arthritis and for postoperative pain.

People also used Carprofen during the 1980s but for commercial reasons, the manufacturer withdrew it from the market, effectively terminating the use of the drug for human treatment.

It’s important to note that the drug does not cause cancer. In a two-year oral toxicity study and an 80-week carcinogenicity study, Carprofen was found to exhibit no carcinogenic potential.

Dosage of Carprofen

When prescribing Carprofen, vets consider both its benefits and risks. To be on the safe side, they often give the minimum effective dosage within the shortest duration possible based on individual response.

In most cases, however, the recommended dose is 2 mg/lb of body weight daily. This can be divided into two daily doses of 1 mg/lb body weight to be given twice daily.

For controlling pain associated with surgery, the drug is usually administered two hours prior to the procedure.

Carprofen is available in capsule as well as tablet forms, in 25, 75, and 100 mg doses. A bottle may contain 30, 60, or 180 capsules depending on size.

Side Effects of Carprofen

There are no clinically significant adverse reactions reported for this NSAID.

In studies, low frequencies of adverse reactions were observed: constipation (3%), behavioral changes (1%), lethargy (1.4%), changes in appetite (3%), diarrhea (4%), and vomiting (4%).

Dogs respond well to the medication. However, like all NSAIDs, prolonged use can result to liver, gastrointestinal, and kidney problems.

Even by staying within the prescribed dose and duration, your canine companion may still experience loss of appetite and loss of coordination. Other side effects to watch out for include:

  • Increase in thirst
  • Seizures
  • Increase in urination
  • Liver dysfunction characterized by yellowing of eyes
  • Partial or full paralysis
  • Skin changes (scabs, redness, etc.)

Effects recorded for Carprofen overdose include ulcer formation and gastritis. Use the drug with caution if your dog has liver or kidney disease, and in cases of dehydration or bleeding.

The safety of Carprofen has not been established for dogs with bleeding disorders, and for those that are pregnant, or used for breeding purposes, as well as in lactating dogs.

Before using Carprofen, confirm with the vet if your dog has an allergic reaction to aspirin. If such is the case, the vet will most likely avoid prescribing the NSAID.

The same goes for allergic reactions to other NSAIDs such as Tepoxalin and Meloxicam. Allergic reactions result to symptoms such as red or itchy skin, hives, or facial swelling.

Cost of Carprofen

Carprofen is a prescription, non-DEA controlled substance. As in the case of other drugs, it’s safe to use the generic equivalent of branded Carprofen. Yes, you’re going to enjoy lots of savings too if you go generic.

The generic form is cheaper because manufacturers do not have to do the same costly laboratory clinical trials that brand-name companies go through to get FDA approval.

No worries with the generic type, however, as it carries the same active ingredient, has the same strength, and is equally safe. Still, ask your vet if he’s recommending a particular brand.

Now for the price, you will spend less than $0.40 per 75-mg pill if you go for generics.

Some generic medicine vendors offer free shipping for a certain minimum amount of order—for example, free shipping for a total purchase of $49. The lowest price is $0.29, which is for 25-mg pills.

Prices for branded varieties like Novox will almost double your expenses. With Novox, you will spend about $0.75 to $0.89 per pill, depending on the supplier. This usually comes with a free shipping offer though.

Other brand names include Rimadyl, Acticarp, Carprieve, and Vetprofen.

Interaction with other Drugs

There are several drugs that interact with Carprofen:

  • Phenytoin – an anti-epileptic drug
  • Valproic acid – also for treating epilepsy and bipolar order
  • Oral anticoagulants – these are blood thinners to reduce risk for stroke
  • Salicylates – examples of these are Acetaminophen and Ibuprofen
  • Sulfonamides – these are drugs that inhibit bacterial growth
  • Sulfonyurea – used in drugs to control diabetes
  • Phobenecid – a drug that increases uric acid secretion
  • Methotrexate – also called antimetabolites; used to treat certain types of cancer, psoriasis, and rheumatoid arthritis
  • Furosemide – used to reduce abnormally high body fluids
  • Digoxin – used to treat atrial fibrillation
  • Glucocorticoids – these are a class of steroid hormones

If you’re unsure of the content of the drugs that your dogs are currently taking, consult your vet.

Ingredients in Carprofen

Depending on the brand, a Carprofen tablet or pill may also contain the following ingredients:

  • Microcrystalline cellulose
  • Croscarmellose sodium
  • Magnesium stearate
  • Purified stearic acid

How much of these other ingredients are included in a given tablet or pill? Well, the specific formula for each variety of the NSAID is maintained as a trade secret by manufacturers.

Carprofen Alternatives

Consider these alternative treatment options in the event of an emergency and in cases when Carprofen is beyond your reach or simply not suited for your pooch:

  • CBD Oil – This is by far the best alternative there is to Carprofen, with some dog owners even attesting that CBD oil is the safest treatment one can consider for a wide range of diseases.

Aside from pain related to arthritis, canine health issues that can be treated include gastrointestinal diseases, symptoms of cancer, anxiety, stress, nausea, and seizures.

Other reasons for using CBD Oil include: improvement of skin and coat, weight and metabolism support, and lowered risk of cardiovascular disease.

However, keep in mind that drowsiness, reduced blood pressure, and dry mouth should be regularly checked for in dogs that are given this natural NSAID substitute.

  • Deracoxib – Like other NSAIDs, this is indicated for pain and inflammation associated with orthopedic surgery and should not be used on pups younger than four months. Vomiting, decreased appetite, and change in bowel movement are its common side effects.
  • Meloxicam – This is given to ease pain, inflammation, and stiffness stemming from musculoskeletal system disorders. Its side effects include appetite loss, diarrhea, loss of coordination, and skin irritation.